Pepsinogen

A substance which is secreted by the stomach wall and converted into the enzyme pepsin by gastric acid.

Most of the epithelial cells in the stomach are dedicated to secreting mucus, hydrochloric acid or a proenzyme called pepsinogen into the lumen of the stomach. The Chief cells produce pepsinogen which goes up to the gastric lumen where it contacts HCL and is converted to pepsin, a protein digesting enzyme.

IBS Smart Test

• • • Serum Pepsinogen and Gastrin Levels: Reliable Markers to Predict Small Intestinal Bacterial Overgrowth.