2-Naphthylamine

2-naphthylamine is a human carcinogen. It can cause bladder cancer.

2-Naphthylamine is absorbed through the skin and respiratory tract. It's found in cigarette smoke and is suspected to contribute to bladder cancer.

2-Naphthylamine is activated in the liver, but quickly deactivated by conjugation to glucuronic acid. In the bladder, glucuronidase re-activates it by deconjugation, which leads to the development of bladder cancer.

The production of 2-naphthylamine on an industrial scale has been banned due to its carcinogenic effects.

Many scientists believe there is no safe level of exposure to a carcinogen. Such substances may also have the potential for causing reproductive damage in humans