Hydnocarpin
Hydnocarpin is a flavonolignan that is isolated from Hydnocarpus wightiana. It has a CAS number of 51419-48-8.
Hydnocarpin has several properties, including:
- Moderate cytotoxicity on cancer cells
- Inhibiting the growth of *S. aureus*
- Antioxidant and anti-inflammatory properties
- Serving as an MDR reversal agent
Different types of hydnocarpin include:
- (Rac)-Hydnocarpin, which is a flavonoid that exhibits moderate cytotoxicity on cancer cells
- (±)-Hydnocarpin, which can inhibit the growth of *S. aureus*
- Hydnocarpin D (HD), which has antioxidant and anti-inflammatory properties
- (-)-Hydnocarpin, which may serve as an MDR reversal agent
You can buy hydnocarpin from: Biorbyt Ltd, Medchemexpress, Fishersci.com.
Antibacterial
Cancer
- Anti-proliferative activity of hydnocarpin, a natural lignan, is associated with the suppression of Wnt/β-catenin signaling pathway in colon cancer cells.
- Potentiating effect of the flavonolignan (-)-hydnocarpin in combination with vincristine in a sensitive and P-gp-expressing acute lymphoblastic leukemia cell line.