5 Data Resources

From: <a href="https://www.commondataelements.ninds.nih.gov/MECFS.aspx#tab=Data_Standards">https://www.commondataelements.ninds.nih.gov/MECFS.aspx#tab=Data_Standards</a>

The National Institute of Neurological Disorders and Stroke (NINDS) and other Federal agencies and international organizations have the common mission of developing data standards for clinical research. Through the efforts of subject-specific working groups, topic-driven data elements have been created. The first set of <a href="https://www.commondataelements.ninds.nih.gov/Glossary.aspx?term=Common+Data+Element+(CDE)">Common Data Elements (CDEs)</a> for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) was developed in 2017. The Core and Supplemental-Highly Recommended data elements to be used by an investigator when beginning a research study in ME/CFS are listed in the <a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/CDEStartupResource_MECFS.pdf">Start-up Resource Listing</a>.

Many of the CDEs will overlap across study types, which allows for comparisons and meta-analysis across studies. Consistency of the data elements and the CDE formats is kept in order to ensure the ability to transfer critical medical information electronically from one center to another. This consistency also allows for continuity across different disease areas. The goals of the NINDS CDE initiative are to increase the efficiency and effectiveness of clinical research studies and clinical treatment, increase data quality, facilitate data sharing, and help educate new clinical investigators.

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/FAQ.pdf">ME/CFS Common Data Elements Project Frequently Asked Questions</a>

Organized by domains and sub-domains, often used in clinical studies, data standards include:

<ul>

<li>CDEs— Classified as <a href="https://www.commondataelements.ninds.nih.gov/Glossary.aspx?term=Core+CDE">Core</a>, <a href="https://www.commondataelements.ninds.nih.gov/Glossary.aspx?term=Supplemental-Highly+Recommended+CDE">Supplemental - Highly Recommended</a>, <a href="https://www.commondataelements.ninds.nih.gov/Glossary.aspx?term=Supplemental+CDE">Supplemental</a>, or <a href="https://www.commondataelements.ninds.nih.gov/Glossary.aspx?term=Exploratory+CDE">Exploratory</a></li>

<li>CRF Modules— logically organize CDEs for data collection</li>

<li>Guidelines— to provide further information about the CDEs.</li>

</ul>

Please view additional tabs for more information about the development of these CDEs. An overview of all Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) CDE recommendations can be found in the <a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/Myalgic_Encephalomyelitis_Chronic_Fatigue_Syndrome_CDE_Highlight_Summary.pdf">ME/CFS CDE Highlight Summary document</a>.

The outline that follows includes all the CDEs associated with the CRF modules, organized by domain and sub-domain.

NIH Resources

<thead>

<tr>

CRF Module/Guideline by Sub-Domain

</td>

CDEs

</td>

</tr>

</thead>

<tbody>

<tr>

NIH Resources

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1463">National Institutes of Health (NIH) Toolbox </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1647">Patient-Reported Outcomes Measurement Information System (PROMIS) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1462">Quality of Life in Neurological Disorders (Neuro-QOL) </a>

</td>

<td>

N/A

</td>

</tr>

</tbody>

</table>

Overview of Working Group Recommendations

<thead>

<tr>

CRF Module/Guideline by Sub-Domain

</td>

CDEs

</td>

</tr>

</thead>

<tbody>

<tr>

Summary Documents

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/MECFS_Overall_Working_Group_Summary.pdf">ME/CFS Overall Working Group Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/Baseline_Covariate_Information_Subgroup_Summary.pdf">Baseline/Covariate Information Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/Fatigue_Subgroup_Summary.pdf">Fatigue Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/PEM_Subgroup_Summary.pdf">Post-Exertional Malaise Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/Sleep_Subgroup_Summary.pdf">Sleep Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/Pain_Subgroup_Summary.pdf">Pain Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/Neuro_Cog_CNS_Imaging_Subgroup_Summary.pdf">Neurologic/Cognitive/CNS Imaging Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/Autonomic_Subgroup_Summary.pdf">Autonomic Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/Neuroendocrine_Subgroup_Summary.pdf">Neuroendocrine Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/Immune_Subgroup_Summary.pdf">Immune Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/QoL_Functional_Status_CPET_Activity_Subgroup_Summary.pdf">Quality of Life/Functional Status/CPET/Activity Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/Biomarkers_Subgroup_Summary.pdf">Biomarkers Subgroup Summary </a>

</td>

<td>

N/A

</td>

</tr>

</tbody>

</table>

Participant Characteristics

<thead>

<tr>

CRF Module/Guideline by Sub-Domain

</td>

CDEs

</td>

</tr>

</thead>

<tbody>

<tr>

Demographics

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/SharedForms/F1807_General_Core.docx">General Core </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Demographics&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F1807&CrfName=General%20Core">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2767_Demographics.docx">Demographics </a>

</td>

<td>

</td>

</tr>

<tr>

Social Status

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2786_Adult_Employment_And_Education_History.docx">Adult Employment and Education History </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Social%20Status&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2786&CrfName=Adult%20Employment%20and%20Education%20History">CDE Details</a>

</td>

</tr>

</tbody>

</table>

Participant History and Family History

<thead>

<tr>

CRF Module/Guideline by Sub-Domain

</td>

CDEs

</td>

</tr>

</thead>

<tbody>

<tr>

General Health History

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2764_Past_and_Current_Illnesses.docx">Past and Current Illnesses </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=General%20Health%20History&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2764&CrfName=Past%20and%20Current%20Illnesses">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2752_Medical_History_Immune_Module.docx">Medical History - Immune Module </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=General%20Health%20History&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2752&CrfName=Medical%20History%20-%20Immune%20Module">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2739_Reproductive_and_Hormonal_History.docx">Reproductive and Hormonal History </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=General%20Health%20History&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2739&CrfName=Reproductive%20and%20Hormonal%20History">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2766_Exposure_History.docx">Exposure History </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=General%20Health%20History&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2766&CrfName=Exposure%20History">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2760_Family_History.docx">Family Health History </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=General%20Health%20History&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2760&CrfName=Family%20Health%20History">CDE Details</a>

</td>

</tr>

</tbody>

</table>

Disease/Injury Related Events

<thead>

<tr>

CRF Module/Guideline by Sub-Domain

</td>

CDEs

</td>

</tr>

</thead>

<tbody>

<tr>

History of Disease/Injury Event

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2768">DePaul Symptom Questionnaire (DSQ) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2769">ME/CFS Symptom Checklist </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2770">DePaul Pediatric Health Screening Questionnaire </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2695_Fatigue_Visual_Analog_Scale.docx">Fatigue Visual Analog Scale </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=History%20of%20Disease/Injury%20Event&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2695&CrfName=Fatigue%20Visual%20Analog%20Scale">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2722_Neuroendocrine_Hypothalamic_Symptoms.docx">Neuroendocrine/Hypothalamic Symptoms </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=History%20of%20Disease/Injury%20Event&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2722&CrfName=Neuroendocrine/Hypothalamic%20Symptoms">CDE Details</a>

</td>

</tr>

</tbody>

</table>

Assessments and Examinations

<thead>

<tr>

CRF Module/Guideline by Sub-Domain

</td>

CDEs

</td>

</tr>

</thead>

<tbody>

<tr>

Physical/Neurological Examination

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2747_Neurological_Exam.docx">Neurological Exam </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Physical/Neurological%20Examination&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2747&CrfName=Neurological%20Exam">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2759_Physical_Examination.docx">Physical Examination </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Physical/Neurological%20Examination&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2759&CrfName=Physical%20Examination">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2750_Physical_Examination_Immune_Module.docx">Physical Exam - Immune Module </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Physical/Neurological%20Examination&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2750&CrfName=Physical%20Exam%20-%20Immune%20Module">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2708_Polysomnography.docx">Polysomnography (PSG) for ME/CFS </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Physical/Neurological%20Examination&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2708&CrfName=Polysomnography%20(PSG)%20for%20ME/CFS">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2798_Pain_Assessment.docx">Pain Assessment </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Physical/Neurological%20Examination&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2798&CrfName=Pain%20Assessment">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/SharedForms/F2139_Beighton_Score.docx">Beighton Score </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Physical/Neurological%20Examination&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2139&CrfName=Beighton%20Score">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/SharedForms/F1019_Grip_Strength_Fatigue.docx">Grip Strength Fatigue  </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Physical/Neurological%20Examination&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2799&CrfName=Grip%20Strength%20Fatigue">CDE Details</a>

</td>

</tr>

<tr>

Post-Exertional Malaise

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2771_Guidance_for_Core_PEM_Assessment.pdf">Guidance for Core PEM Assessment </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2698_Core_PEM_Assessment_Questionnaire.docx">Core PEM Assessment Questionnaire </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Post-Exertional%20Malaise&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2698&CrfName=Core%20PEM%20Assessment%20Questionnaire">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2792_Guidance_for_PEM_Focused_Studies.pdf">Guidance for PEM-Focused Studies </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2697_PEM_Focused_Studies_Questionnaire.docx">PEM-Focused Studies Questionnaire </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Post-Exertional%20Malaise&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2697&CrfName=PEM-Focused%20Studies%20Questionnaire">CDE Details</a>

</td>

</tr>

<tr>

Exercise Physiology

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2709_Cardiopulmonary_Exercise_Testing_(CPET).docx">Cardiopulmonary Exercise Testing (CPET) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Exercise%20Physiology&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2709&CrfName=Cardiopulmonary%20Exercise%20Testing%20(CPET)">CDE Details</a>

</td>

</tr>

<tr>

Autonomic

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1659">Composite Autonomic Symptom Scale </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2719_Modified_Orthostatic_Symptom_Grading_Scale.docx">Modified Orthostatic Symptom Grading Scale </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Autonomic&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2719&CrfName=Modified%20Orthostatic%20Symptom%20Grading%20Scale">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2791_Passive_Standing_Test_Protocol.docx">Passive Standing Test Protocol </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Autonomic&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2791&CrfName=Passive%20Standing%20Test%20Protocol">CDE Details</a>

</td>

</tr>

<tr>

Laboratory Tests and Biospecimens/Biomarkers

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2758_Laboratory_Test_Results.docx">Laboratory Test Results </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Laboratory%20Tests%20and%20Biospecimens/Biomarkers&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2758&CrfName=Laboratory%20Test%20Results">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2765_Laboratory_Tests_Immune_Module.docx">Laboratory Tests - Immune Module </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Laboratory%20Tests%20and%20Biospecimens/Biomarkers&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2765&CrfName=Laboratory%20Tests%20-%20Immune%20Module">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2713_Neuroendocrine_Labs.docx">Neuroendocrine Labs </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Laboratory%20Tests%20and%20Biospecimens/Biomarkers&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2713&CrfName=Neuroendocrine%20Labs">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2795_Biomarkers_Guidelines.pdf">Biomarkers Guidelines </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2796_Biomarkers_Reference_Table.pdf">Biomarkers Reference Table </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2743_Biomarker-Related_Sample_and_Collection_Questions.docx">Biomarker-Related Sample and Collection Questions </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Laboratory%20Tests%20and%20Biospecimens/Biomarkers&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2743&CrfName=Biomarker-Related%20Sample%20and%20Collection%20Questions">CDE Details</a>

</td>

</tr>

<tr>

Imaging Diagnostics

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2793_Special_Imaging_Considerations.pdf">Special Imaging Considerations </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2794_Suggested_Parameters_for_MRI_Scans.pdf">Suggested Parameters for Common Magnetic Resonance Imaging (MRI) Scans </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2753_Magnetic_Resonance_Imaging.docx">Magnetic Resonance Imaging (MRI) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Imaging%20Diagnostics&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2753&CrfName=Magnetic%20Resonance%20Imaging%20(MRI)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2756_Functional_Magnetic_Resonance_Imaging_(fMRI).docx">Functional Magnetic Resonance Imaging (fMRI) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Imaging%20Diagnostics&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2756&CrfName=Functional%20Magnetic%20Resonance%20Imaging%20(fMRI)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2748_Diffusion_Tensor_Imaging.docx">Diffusion Tensor Imaging (DTI) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Imaging%20Diagnostics&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2748&CrfName=Diffusion%20Tensor%20Imaging%20(DTI)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2757_Magnetic_Resonance_Spectroscopy_(MRS).docx">Magnetic Resonance Spectroscopy (MRS) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Imaging%20Diagnostics&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2757&CrfName=Magnetic%20Resonance%20Spectroscopy%20(MRS)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2754_Positron_Emission_Tomography_(PET).docx">Positron Emission Tomography (PET) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Imaging%20Diagnostics&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2754&CrfName=Positron%20Emission%20Tomography%20(PET)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2755_Magnetoencephalography.docx">Magnetoencephalography (MEG) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Imaging%20Diagnostics&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2755&CrfName=Magnetoencephalography%20(MEG)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2749_Non-Quantitative_Electroencephalography_(EEG).docx">Non-Quantitative Electroencephalography (EEG) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Imaging%20Diagnostics&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2749&CrfName=Non-Quantitative%20Electroencephalography%20(EEG)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2762_Quantitative_Electroencephalography_(qEEG).docx">Quantitative Electroencephalography (qEEG) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Imaging%20Diagnostics&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2762&CrfName=Quantitative%20Electroencephalography%20(qEEG)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2763_Low_Resolution_Electromagnetic_Tomography_(LORETA).docx">Low Resolution Electromagnetic Tomography (LORETA) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Imaging%20Diagnostics&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2763&CrfName=Low%20Resolution%20Electromagnetic%20Tomography%20(LORETA)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2797_ME_CFS_Functional_Imaging_Task_Summaries.pdf">ME/CFS Functional Imaging Task Summaries </a>

</td>

<td>

N/A

</td>

</tr>

</tbody>

</table>

Treatment/Intervention Data

Note: The <a href="https://www.commondataelements.ninds.nih.gov/General.aspx">General CDE Standards</a> contain useful CRF Modules and CDEs for this domain.

<thead>

<tr>

CRF Module/Guideline by Sub-Domain

</td>

CDEs

</td>

</tr>

</thead>

<tbody>

<tr>

Drugs

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2751_Medication_and_Other_Treatments.docx">Medication and Other Treatments </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Drugs&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2751&CrfName=Medication%20and%20Other%20Treatments">CDE Details</a>

</td>

</tr>

</tbody>

</table>

Protocol Experience

Note: The <a href="https://www.commondataelements.ninds.nih.gov/General.aspx">General CDE Standards</a> contain useful CRF Modules and CDEs for this domain.

Safety Data

Note: The <a href="https://www.commondataelements.ninds.nih.gov/General.aspx">General CDE Standards</a> contain useful CRF Modules and CDEs for this domain.

Outcomes and End Points

<thead>

<tr>

CRF Module/Guideline by Sub-Domain

</td>

CDEs

</td>

</tr>

</thead>

<tbody>

<tr>

Summary of All Outcome Measure Recommendations

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2788_Cognitive_Instrument_Summary_Classification.pdf">Cognitive Subgroup Instrument Summary by Classification </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2789_Cognitive_Instrument_Summary_Subdomain.pdf">Cognitive Subgroup Instrument Summary by Subdomain </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

Academic Achievement

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2699">Word Reading Subtest of the Wide Range Achievement Test (WRAT-4) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Academic%20Achievement&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2699&CrfName=Word%20Reading%20Subtest%20of%20the%20Wide%20Range%20Achievement%20Test%20(WRAT-4)">CDE Details</a>

</td>

</tr>

<tr>

Activities of Daily Living/Performance

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2696_Fatigue_Activity_Record_Diary.docx">Fatigue/Activity Record and Diary </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Activities%20of%20Daily%20Living/Performance&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2696&CrfName=Fatigue/Activity%20Record%20and%20Diary">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2805">Modifiable Activity Questionnaire (MAQ) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2742_Physical_Functioning_Activities_Daily_Living.docx">Physical Functioning and Activities of Daily Living </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Activities%20of%20Daily%20Living/Performance&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2742&CrfName=Physical%20Functioning%20and%20Activities%20of%20Daily%20Living">CDE Details</a>

</td>

</tr>

<tr>

Attention/Information Processing

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2700">Paced Auditory Serial Addition Test (PASAT) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1633">Automated Neuropsychological Assessment Metrics (ANAM) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Attention/Information%20Processing&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F1633&CrfName=Automated%20Neuropsychological%20Assessment%20Metrics%20(ANAM)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2772">Deary-Liewald Reaction Time Task </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1255">Stroop Test </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Attention/Information%20Processing&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F1255&CrfName=Stroop%20Test">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1503">Test of Variables of Attention (TOVA) </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2701">Children's Paced Auditory Serial Addition Task (ChiPASAT) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

Emotional/Behavioral

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2703">Beck Anxiety Inventory (BAI) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Emotional/Behavioral&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2703&CrfName=Beck%20Anxiety%20Inventory%20(BAI)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F0372">Center for Epidemiologic Studies-Depression Scale (CES-D) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Emotional/Behavioral&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F0372&CrfName=Center%20for%20Epidemiologic%20Studies-Depression%20Scale%20(CES-D)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1392">State-Trait Anxiety Inventory (STAI) </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2704">Beck Depression Inventory II (BDI-II) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Emotional/Behavioral&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2704&CrfName=Beck%20Depression%20Inventory%20II%20(BDI-II)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2572">Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version (K-SADS-PL) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Emotional/Behavioral&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2572&CrfName=Kiddie-Schedule%20for%20Affective%20Disorders%20and%20Schizophrenia-Present%20and%20Lifetime%20Version%20(K-SADS-PL)">CDE Details</a>

</td>

</tr>

<tr>

Executive Functioning

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1450">Delis-Kaplan Executive Function System (D-KEFS) </a> © ™

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2016">NIH Toolbox Cognitive Battery </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Executive%20Functioning&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2016&CrfName=NIH%20Toolbox%20Cognitive%20Battery">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2396">Cambridge Neuropsychological Test Automated Battery (CANTAB) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2712">Cogstate Tests </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

Fatigue

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2714">Fatigue Severity Scale (FSS) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Fatigue&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2714&CrfName=Fatigue%20Severity%20Scale%20(FSS)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2715">Checklist for Individual Strength - Fatigue (CIS)  </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Fatigue&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2715&CrfName=Checklist%20for%20Individual%20Strength%20-%20Fatigue%20(CIS)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2716">Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2717">Wood Mental Fatigue Inventory </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1926">Pediatric Quality of Life Inventory, Multidimensional Fatigue Scale </a> ™

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1321">PROMIS Fatigue Short Form </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2724">Neuro-QOL Adult Bank - Fatigue </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Fatigue&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2724&CrfName=Neuro-QOL%20Adult%20Bank%20-%20Fatigue">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1026">Modified Fatigue Impact Scale (MFIS) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Fatigue&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F1026&CrfName=Modified%20Fatigue%20Impact%20Scale%20(MFIS)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2720">Multidimensional Fatigue Inventory (MFI) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

Intellectual Functioning

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2702">Edinburgh Handedness Inventory </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2761">North American Adult Reading Test (NAART) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2522">Test of Premorbid Functioning </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Intellectual%20Functioning&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2522&CrfName=Test%20of%20Premorbid%20Functioning">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1467">Wechsler Adult Intelligence Scale - Fourth Edition (WAIS-IV) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Intellectual%20Functioning&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F1467&CrfName=Wechsler%20Adult%20Intelligence%20Scale%20-%20Fourth%20Edition%20(WAIS-IV)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2744">Wechsler Abbreviated Scale of Intelligence - Second Edition (WASI-II) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Intellectual%20Functioning&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2744&CrfName=Wechsler%20Abbreviated%20Scale%20of%20Intelligence%20-%20Second%20Edition%20(WASI-II)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2721">Woodcock-Johnson III Test of Cognitive Abilities </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Intellectual%20Functioning&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2721&CrfName=Woodcock-Johnson%20III%20Test%20of%20Cognitive%20Abilities">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1456">Wechsler Intelligence Scale for Children-V (WISC-V) </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

Memory

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2723">California Verbal Learning Test - Second Edition (CVLT-II) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Memory&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2723&CrfName=California%20Verbal%20Learning%20Test%20-%20Second%20Edition%20(CVLT-II)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1866">Wechsler Memory Scale IV (WMS-IV) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Memory&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F1866&CrfName=Wechsler%20Memory%20Scale%20IV%20(WMS-IV)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1471">Rey-Osterrieth Complex Figure Test (ROCF) </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2726">California Verbal Learning Test - Children (CVLT-C) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Memory&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2726&CrfName=California%20Verbal%20Learning%20Test%20-%20Children%20(CVLT-C)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2725">Children's Memory Scale (CMS) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

Motor Function

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1253">Speeded Tapping Test </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

Pain

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2727">Brief Pain Inventory (Short Form) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Pain&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2727&CrfName=Brief%20Pain%20Inventory%20(Short%20Form)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2728">Revised Fibromyalgia Impact Questionnaire (FIQR) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1315">McGill Pain Questionnaire (MPQ) </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2114">Faces Pain Scale - Revised </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2729">Pain Frequency-Severity-Duration Scale (PFSD) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1773">Neuropathic Pain Symptom Inventory (NPSI) </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1322">PROMIS Pain Interference Short Form </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2790">PROMIS Pain Behavior Short Form </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

Quality of Life/Patient Reported Outcomes

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2730">Mental Fatigue Scale (MFS) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2170">Short Form 36-Item Health Survey (SF-36) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Quality%20of%20Life/Patient%20Reported%20Outcomes&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2170&CrfName=Short%20Form%2036-Item%20Health%20Survey%20(SF-36)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1484">Child Health Questionnaire (CHQ) </a> ™

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1384">Functional Disability Inventory - Child and Adolescent Form (FDI) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Quality%20of%20Life/Patient%20Reported%20Outcomes&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F1384&CrfName=Functional%20Disability%20Inventory%20-%20Child%20and%20Adolescent%20Form%20(FDI)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1383">Functional Disability Inventory - Parent Form (FDI) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Quality%20of%20Life/Patient%20Reported%20Outcomes&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F1383&CrfName=Functional%20Disability%20Inventory%20-%20Parent%20Form%20(FDI)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2741">Bell CFIDS Disability Scale </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Quality%20of%20Life/Patient%20Reported%20Outcomes&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2741&CrfName=Bell%20CFIDS%20Disability%20Scale">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2731">EuroQoL-5 Dimension Questionnaire (EQ-5D) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Quality%20of%20Life/Patient%20Reported%20Outcomes&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2731&CrfName=EuroQoL-5%20Dimension%20Questionnaire%20(EQ-5D)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1408">Health Related Quality of Life-14 (HRQOL-14) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2740">Karnofsky Performance Scale </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Quality%20of%20Life/Patient%20Reported%20Outcomes&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2740&CrfName=Karnofsky%20Performance%20Scale">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F1511">World Health Organization Disability Assessment Schedule (WHODAS)  </a> ©

</td>

<td>

N/A

</td>

</tr>

<tr>

Sleep

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2706_Sleep_Questions_For_All_Studies.docx">Sleep Questions For All Studies </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Sleep&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2706&CrfName=Sleep%20Questions%20For%20All%20Studies">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/Doc/MECFS/F2707_Sleep_Focused_Study.docx">Sleep Focused Study Questionnaire </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Sleep&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2707&CrfName=Sleep%20Focused%20Study%20Questionnaire">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2732">Sleep Assessment Questionnaire - Moldofsky </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2123">Pittsburgh Sleep Quality Index (PSQI) </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Sleep&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2123&CrfName=Pittsburgh%20Sleep%20Quality%20Index%20(PSQI)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F0798">Stanford Sleepiness Scale (SSS) </a> ©

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Sleep&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F0798&CrfName=Stanford%20Sleepiness%20Scale%20(SSS)">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2733">Sleep Disorders Screening Checklist </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2734">Holland Sleep Disorders Questionnaire (HSDQ) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2592">Epworth Sleepiness Scale (ESS) – Children’s Version </a>

</td>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptAllCDE&rs:Command=Render&rc:Parameters=false&CDEName=&DiseaseName=Myalgic%20Encephalomyelitis/Chronic%20Fatigue%20Syndrome&SubDiseaseName=&DomainName=+&SubDomainName=Sleep&Classification=+&IsCopyright=&Population=+&CdeId=+&keyword=&CrfId=F2592&CrfName=Epworth%20Sleepiness%20Scale%20(ESS)%20%E2%80%93%20Children%E2%80%99s%20Version">CDE Details</a>

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2735">Nonrestorative Sleep Scale (NRSS) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2736">Global Sleep Assessment Questionnaire (GSAQ) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2737">Restorative Sleep Questionnaire (RSQ) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

<td>

<a href="https://www.commondataelements.ninds.nih.gov/ReportViewer.aspx?/nindscdereports/rptNOC&rs:Command=Render&rc:Parameters=false&crfID=F2107">Adolescent Sleep Hygiene Scale (ASHS) </a>

</td>

<td>

N/A

</td>

</tr>

<tr>

Visual-Spatial Processing

</td>

</tr>

<tr>

<td>

</td>

<td>

N/A

</td>

</tr>

</tbody>

</table>

To develop the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) CDEs, the <a class=" inactive" href="https://www.commondataelements.ninds.nih.gov/MECFS.aspx#History_and_Acknowledgements">Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Working Groups</a> are divided into 11 subgroups to focus on identifying and defining data elements in the domains of:

<ul>

<li>Baseline/Covariate</li>

<li>Fatigue</li>

<li>Post-Exertional Malaise</li>

<li>Sleep</li>

<li>Neurologic/Cognitive/CNS Imaging</li>

<li>Autonomic</li>

<li>Neuroendocrine</li>

<li>Immune</li>

<li>QOL/Functional Status/CPET/Activity</li>

<li>Biomarkers</li>

</ul>

Data standards include CDEs as well as case report form (CRF) Modules and Guidelines. The CRF Modules logically organize the CDEs for data collection, while the Guidelines provide further information about the CDEs. The CDEs, CRF Modules, and Guidelines presented are organized into domains which are intuitive and common in clinical research studies.