Radio

<p>This is when I discovered Dr. Amy Yasko's work on autism and nutrigenomics. I studied her work, as well as Dr. Sarah Myhill's. I also referenced Fred Davis' protocol and began the extensive research needed to heal my self at any cost. I developed my own recovery protocol. I started feeling better. In eight weeks, combined with my anti-inflammatory diet and mitochondria support, I regained my energy and fully recovered from chronic fatigue. I hope my story can inspire others to see that recovery is possible.<br />

<b >

Hypochlorhydria + Dysbiosis + Chronic inflammation = Acquired Mitochondrial Damage</b><br />

<br />

I am convinced that the toxic waste produced by the pathogenic bacteria can be very damaging, especially when we are not methylating RNA, DNA and phosphatidylcholine. Acquired mitochondria damage is a normal part of aging and for unknown reasons is accelerated in this syndrome. The immune system and viral infections are in the crossfire in this metabolic disaster. There needs to be a balance in methylation and gut fermentation. The human microbiome and the methylation cycle are connented at the hip in a manner of speaking. We do have some understanding of the methylation at this point. We are in the dark ages when it comes to human microbiome. We need more information on dysbiosis relating to methylation and environmental factors. The immune system and the mitochondria are critical in these metabolic imbalances.<br />

<br />

<b >

What is the root cause of the dysbiosis imbalance? </b><br />

<br />

Let's add in H-pylori and gastritis into the mix. H-pylori infection can dramatically reduces stomach acid. This could be the main problem contributing to dysbiosis imbalances. Hydrochloric acid deficiency and heavy metal toxicity can be a issue in this dysfunctional metabolism. The body needs (HCL) to help make minerals and nutrients more absorbable and to achieve the correct flora balance. Stomach acid is also required to liberate vitamin B12 from food. Intestinal bacterial overgrowth can produce histamine, hydrogen sulfide, hydrogen peroxide, tryptophanase, d-lactic acid and endotoxins. This could be the root cause of this metabolic damage. We need to build a diet and treatment protocol that fits in perfect harmony with nature's grand design of health and wellness.<br />

<br />

<b >

The TRUTH about Stomach Acid! </b><br />

<br />

<b >Dysbiosis, Inflammation, Autoimmunity: Lupus, Rheumatoid Arthritis, Psoriasis, Sjogrens syndrome</b><br />

<b >

Small intestine bacterial overgrowth (SIBO, dysbiosis) causes Fibromyalgia (corrected version) </b><br />

<b >

Alex Vasquez, D.C., N.D.</b><br />

<a href="http://www.academia.edu/3862817/Nutritional_and_Botanical_Treatments_Against_Silent_Infections_and_Gastrointestinal_Dysbiosis_Commonly_Overlooked_Causes_of_Neuromusculoskeletal_Inflammation_and_Chronic_Health_Problems" target="_blank" class="externalLink" rel="nofollow" >http://www.academia.edu/3862817/Nut...etal_Inflammation_and_Chronic_Health_Problems</a><br />

<b >

Hypochlorhydria lack of stomach acid - can cause lots of problems</b><br />

<a href="http://drmyhill.co.uk/wiki/Hypochlorhydria-lack_of_stomach_acid-can_cause_lots_of_problems" target="blank" class="externalLink" rel="nofollow" >http://drmyhill.co.uk/wiki/Hypochlorhydria-lack_of_stomach_acid _can_cause_lots_of_problems</a><br />

<b >Hypochlorhydria / Wiki</b><br />

<a href="http://en.wikipedia.org/wiki/Achlorhydria" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Achlorhydria</a><br />

<b >Salivary test for hypochlorhydria</b><br />

<a href="http://drmyhill.co.uk/wiki/Vascular_endothelial_growth_factor%28VEGF%29-salivary_test_for_hypochlorhydria" target="blank" class="externalLink" rel="nofollow" >http://drmyhill.co.uk/wiki/Vascular_endothelial_growth_factor(VEGF)-_salivary_test_for_hypochlorhydria</a><br />

<b >Helicobacter Pylori: Not Just A Third World Problem?</b><a href="http://www.stopthethyroidmadness.com/h-pylori/" target="_blank" class="externalLink" rel="nofollow" > http://www.stopthethyroidmadness.com/h-pylori/</a><br />

<b >Gastritis / Wiki</b><br />

<a href="http://en.wikipedia.org/wiki/Gastritis" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Gastritis</a><br />

<b >

Dr. Myhill, Hydrogen Sulfide</b><br />

<br />

 </p>

<aside>

<div class="quote" ><b>TOO MUCH CAN BE VERY TOXIC</b>

In excess, H2S acts as a mitochondrial poison inhibiting many <a href="http://www.ei-resource.org/#" target="blank" class="externalLink" rel="nofollow" >enzymes</a> involved in oxidative phosphorylation [manufacture by the mitochondria of energy in the form of ATP]. It also interferes with oxygen transport in <a href="http://www.ei-resource.org/#" target="blank" class="externalLink" rel="nofollow" >red blood cells</a>, a little bit like carbon monoxide. Almost always we see low levels of glutathione in CFS, which is a sulfur containing molecule.

From an evolutionary perspective, mitochondria are organelles descended from ancient eukaryotic sulfur-using microbes, and so it is not surprising that H2S targets mitochondria. H2S inhibits immune cells such as CD8, T cells, and Natural Killer cells, so contributing to the immune dysfunction. It also impacts on the hypothalamic-pituitary-adrenal axis. It regulates the use of oxygen by mitochondria.

When gut bacteria or fungi are attacked by something like a heavy metal molecule (e.g. mercury), they have a special defense mechanism (called a "resistance gene") that produces Hydrogen Sulfide (H2S) gas, which binds to the attacker and neutralizes it. Subsequently this highly toxic and poisonous H2S gas is created in the gut. H2S can impair the immunity system, especially in the area of neutrophil function, which is used to fight the original yeast in the gut, and hence one can hit a vicious cycle. H2S is very similar to mercury, in that it can bind to many of the things that mercury binds to and inactivate them. In other words, all the bad things that mercury can do, as described <a href="http://www.beatcfsandfms.org/html/HgRootCause.html" target="blank" class="externalLink" rel="nofollow" >here</a>, H2S can do. H2S can also convert the safer Inorganic mercury to the more dangerous Organic mercury, as described <a href="http://www.beatcfsandfms.org/html/CheckForHg.html#TwoKindsOfHg" target="blank" class="externalLink" rel="nofollow" >here</a>. H2S has a very special circular relationship with the heavy metals; and therefore, it is a very special gas.

<aside>

Fermentation in the gut and CFS</b>

<a href="http://www.drmyhill.co.uk/wiki/Fermentation_in_the_gut_and_CFS" target="_blank" class="externalLink" rel="nofollow" >http://www.drmyhill.co.uk/wiki/Fermentation_in_the_gut_and_CFS</a>

<b>Multifocal Dysbiosis: Treatment With Nutritional and Botanical Interventions</b>

<a href="http://www.naturopathydigest.com/archives/2006/jun/vasquez.php" target="_blank" class="externalLink" rel="nofollow" >http://www.naturopathydigest.com/archives/2006/jun/vasquez.php</a></div>

</blockquote>

</aside>

</div>

</blockquote>

</aside>

</div>

<p><b>

Mitochondria Cytochrome C Oxidase Connection</b><br />

 </p>

<aside>

<div class="quote" ><b>Inhibition</b>

<a href="http://en.wikipedia.org/wiki/Hydrogen_sulfide" target="blank" class="externalLink" rel="nofollow" >Sulfide</a>, and <a href="http://en.wikipedia.org/wiki/Carbon_monoxide" target="blank" class="externalLink" rel="nofollow" >carbon monoxide</a> all bind to cytochrome c oxidase, thus <a href="http://en.wikipedia.org/wiki/Competitive_inhibition" target="blank" class="externalLink" rel="nofollow" >competitively</a> inhibiting the protein from functioning, which results in chemical <a href="http://en.wikipedia.org/wiki/Asphyxiation" target="blank" class="externalLink" rel="nofollow" >asphyxiation</a> of cells. <a href="http://en.wikipedia.org/wiki/Methanol" target="blank" class="externalLink" rel="nofollow" >Methanol</a> in <a href="http://en.wikipedia.org/wiki/Denatured_alcohol" target="blank" class="externalLink" rel="nofollow" >methylated spirits</a> is converted into <a href="http://en.wikipedia.org/wiki/Formic_acid" target="_blank" class="externalLink" rel="nofollow" >formic acid</a>, which also inhibits the same oxidase system.</div>

</blockquote>

</aside>

</div>

<p><b >

Cytochrome c oxidase</b><br />

<a href="http://en.wikipedia.org/wiki/Cytochrome_c_oxidase" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Cytochrome_c_oxidase</a><br />

<br />

 </p>

<aside>

<div class="quote" >The myelin sheath is made of phospholipids whose synthesis depends on cytochrome <i>c</i> oxidase activity.</div>

</blockquote>

</aside>

</div>

<a href="http://lpi.oregonstate.edu/infocenter/minerals/copper/" target="_blank" class="externalLink" rel="nofollow" >http://lpi.oregonstate.edu/infocenter/minerals/copper/</a><br />

<br />

 </p>

<aside>

<div class="quote" ><b>Hydrogen sulfide</b> activates <a href="http://en.wikipedia.org/wiki/ATP-sensitive_potassium_channel" target="_blank" class="externalLink" rel="nofollow" >ATP-sensitive potassium channels</a> in smooth muscle cells. Researchers are not clear how the vessel-relaxing responsibilities are shared between nitric oxide and hydrogen sulfide.</div>

</blockquote>

</aside>

</div>

<p><b >

Hydrogen sulfide </b><a href="http://en.wikipedia.org/wiki/Hydrogen_sulfide" target="_blank" class="externalLink" rel="nofollow" >wikipedia.org/wiki/Hydrogen_sulfide</a><br />

<br />

 </p>

<aside>

<div class="quote" ><b>Histotoxic hypoxia </b>is the inability of cells to take up or utilize oxygen from the bloodstream, despite physiologically normal delivery of oxygen to such cells and tissues. Histotoxic hypoxia results from tissue poisoning, such as that caused by <a href="http://en.wikipedia.org/wiki/Alcohol" target="blank" class="externalLink" rel="nofollow" >alcohol</a>, <a href="http://en.wikipedia.org/wiki/Narcotics" target="blank" class="externalLink" rel="nofollow" >narcotics</a>, <a href="http://en.wikipedia.org/wiki/Cyanide" target="blank" class="externalLink" rel="nofollow" >cyanide</a> (which acts by inhibiting <a href="http://en.wikipedia.org/wiki/Cytochrome_oxidase" target="blank" class="externalLink" rel="nofollow" >cytochrome oxidase</a>), and certain other <a href="http://en.wikipedia.org/wiki/Poison" target="blank" class="externalLink" rel="nofollow" >poisons</a> like <a href="http://en.wikipedia.org/wiki/Hydrogen_sulfide" target="blank" class="externalLink" rel="nofollow" >hydrogen sulfide</a>.

Histotoxic hypoxia refers to a reduction in ATP production by the mitochondria due to a defect in the cellular usage of oxygen.There is a profound drop in tissue oxygen consumption since the reaction of oxygen with cytochrome c oxidase is blocked.

Histotoxic literally means that the cells have been poisoned. There is no problem getting the oxygen to the tissue - the lungs, blood and circulatory system are all working just fine. However, the tissue is <b>unable to use the oxygen</b>. Even though there is plenty of oxygen there, the cells experience a lack of oxygen and are affected as if there was too little/no oxygen available.</div>

</blockquote>

</aside>

</div>

<p><b >

Histotoxic Hypoxia</b><br />

<a href="http://en.wikipedia.org/wiki/Histotoxic_hypoxia" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Histotoxic_hypoxia</a><br />

<b >Oxidative phosphorylation</b><br />

<a href="http://en.wikipedia.org/wiki/Oxidative_phosphorylation" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Oxidative_phosphorylation</a><br />

<br />

 </p>

<aside>

<div class="quote" ><b>RichVank,</b>

"Hydrogen sulfide (H2S) has been getting more attention lately in connection with CFS."

"As I think many of you know, the methylation cycle and glutathione are both parts of the overall sulfur metabolism in the body, as is the production of H2S."

"The various reactions that can produce H2S in the body include parts of the

human metabolism, and also the metabolism of certain bacteria in the gut."

"The first place I heard about H2S in connection with CFS was from Dr. Amy Yasko, who emphasizes that people who have genetic polymorphisms in their cystathionine beta synthase (CBS) enzyme, along with a methylation cycle block, will tend to generate more H2S."

"I also heard about sulfur-related topics from Susan Owens, who runs the Yahoo sulfurstories group and the group about trouble with Epsom salts. On the latter topic, I have speculated that people who don't tolerate Epsom salts well may have sulfate-reducing bacteria (SRBs) in their gut, which convert sulfate to hydrogen sulfide. SRBs have been found in the gut in some people. As far as I know, the human metabolism does not have a pathway for chemically reducing sulfate, so I think the bacteria must be responsible for converting the sulfate to more chemically reduced species, such as H2S and eventually sulfite, and thus producing the sulfate intolerance in these people. Sulfate is the main form of sulfur normally excreted in the urine."

<b>"In the human metabolism, the two enzymes of the transsulfuration pathway, i.e. cystathionine beta synthase (CBS) and cystathionine gamma lyase (CGL), akacystathionase, are capable of producing H2S from cysteine or homocysteine."</b>

"In my 2008 revision of the Glutathione Depletion--Methylation Cycle Block hypothesis, described in the set of PowerPoint slides in the files section of the cfs-yasko group's website, I proposed that cysteine becomes oxidized to cystine inthe oxidative stress condition present in CFS, and that CGL then catalyzes a pathway starting with cystine that produces hydrogen sulfide and thiosulfate. I based this on research summarized by Martha Stipanuk, who has worked a lot in this area with rats."

"I just heard a few days ago from Prof. Ruma Banerjee, who is probably the leading researcher in the area involving the human sulfur metabolism and vitamin B12, that the human version of CGL does not use cystine as a substrate under normal conditions, which the rat version does. I'm not sure yet whether it would do so under oxidizing conditions, so this aspect of my hypothesis is stilla little "up in the air" at this point. It is clear from our clinical study (alsoin the files section of the cfs-yasko website) that the methylation cycle block in CFS is linked to glutathione depletion, so there has to be away to explain where the sulfur metabolites that are dumped down the transsulfuration pathway when there is a methylation cycle block actually go, since they don't go into making more glutathione. This aspect needs more research."

"Marian Lemle has proposed that hydrogen sulfide is involved in CFS. I had the privilege of meeting her at the Reno conference in March, where we both presented poster papers. She is also a friend of Prof. Dick Deth, who works primarily on autism, and who is very knowledgeable about the sulfur metabolism. Marian got her paper published in the journal Medical Hypotheses, and she also presented her hypothesis to the federal CFS Advisory Committee last October. Marian didn't get into the biochemistry of how H2S is produced (she is a science writer, not a scientist per se), but she noted that the symptoms of H2S poisoning are similar to those of CFS, and that was the basis for her hypothesis that H2S is involved in CFS. I thought this was interesting work, and I have interacted with her concerning how her work and mine might be connected."

"Dr. de Meirleir and his group have found that hydrogen sulfide is elevated in the urine in the most severely ill M.E. patients, and his company is now offering a qualitative urine test for H2S. His view seems to be that the H2S is being produced by bacteria in the gut in the severely ill patients, and I think he is probably right about that."

"I think that we will eventually be able to tie all of this together, but it will take some careful lab work to nail it down."

"Here are some speculations about what goes on: First, the sulfur in the human body originates in the diet (and supplements, if they are used). It comes in assulfur-containing amino acids (methionine, cysteine, cystine, and taurine), and also in the form of sulfate and a few other sulfur-containing species. The sulfur in whatever amount of H2S is produced, by either the human metabolism or the bacteria in the gut, must originate in the diet (and supplements) People who bathe in Epsom salts will absorb some sulfate through their skin."

"In a normal, healthy person, a lot of the sulfur-containing substances are digested in the gut and are absorbed into the blood, while some remain in the gut. Also, some are transported into the gut via the bile, from the liver."

"Bacteria in the gut therefore have access to some of it, and I think we are all familiar with the rotten egg smell that can be associated with flatus, which comes from hydrogen sulfide. So it is not unusual for bacteria in the gut to be producing hydrogen sulfide."

"It is quite common in CFS that there is dysfunction in the digestive system.This can include low stomach acid, slow gastric motility, insufficient secretion of pancreatic enzymes, insufficient secretion of bile, gluten or casein sensitivity,fructose or lactose intolerance, candidiasis, dysbiotic bacteria, intestinal permeability (leaky gut), a variety of other food sensitivities, secretory IgA deficiency, protozoal or helminthic parasites, and others."

"Under these circumstances, I think it is quite likely that less of the sulfur containing substances will be absorbed into the blood, and more will be metabolized by bacteria in the gut. The results would likely be less methionine available for the body's use (including for the methylation cycle), and more hydrogen sulfide produced by bacteria in the gut, which can be absorbed into the blood, have toxic effects on the cells of the body, and be excreted in the urine."

"As I noted in a recent post, some of the people who have not responded to the simplfied treatment approach for lifting the methylation cycle block appear to be low in methionine. If there is not enough methionine available, the methylation cycle will operate slowly, even if the partial block has been lifted, because there is not enough "cargo" to be carried around this cycle or to feed the transsulfuration pathway."

"I think this fits in well with what Dr. de Meirleir has reported. If sulfur-containing substances aren't being absorbed into the body, they would be available to feed the bacteria in the gut."

"I've also noted that in some of the most severely ill PWCs, the condition of the gut is so dysfunctional that they are not able to derive much nutrition from their food. Again, I think this is consistent."

"So what does this mean for treatment? I think it means that if a person is relatively well, the simplified treatment approach is likely to work. If their methionine is low, they may also need to supplement it, or to increase their protein intake in general, perhaps together with betaine HCl to augment stomach acid and digestive enzymes to help break down the protein in the gut, so that the amino acids can be absorbed."

"If a person is severely ill, so that the digestive system is no longer able to deliver much nutrition to their body, then I think it is likely that the hydrogen sulfide level in their urine will be elevated, as Dr. de Meirleir has reported, because the absorption of the sulfur-containing substances will be lowered. In these cases, it seems reasonable to suspect that many of the serious symptoms that are experienced are effects of hydrogen sulfide. Also in these cases, there may need to be intravenous feeding until the gut is in better condition, and the simplified treatment approach may not help until the gut is

in condition to absorb nutrients, and the methionine level is high enough that the methylation cycle is being fed with it."

"So how do we know where to draw the line between cases in which the simplified treatment will work, and cases that will require additional efforts? I think that measuring the methionine level in a urine amino acids test is one thing that can be done, and perhaps the H2S test being offered by Dr. de Meirleir's company would be another way to gauge this. This is all very new, so we don't have experience to go on yet, but I do think all of this will fit together."

Best regards,

Rich</div>

</blockquote>

</aside>

</div>

<br />

<b >Interview: Ian Lipkin’s Million Dollar Appeal for Microbiome Study</b><br />

<a href="http://forums.phoenixrising.me/index.php?threads/interview-ian-lipkin%E2%80%99s-million-dollar-appeal-for-microbiome-study.28139/" class="internalLink" >http://forums.phoenixrising.me/index.php?threads/interview-ian-lipkin’s-million-dollar-appeal-for-microbiome-study.28139/</a><br />

<b >

In CFS/ME, Professor De Meirleir treats diet first. Then he treats abnormal gut flora. He says it takes a year to recover gut function.</b> <a href="http://cfstreatment.blogspot.com/2013/01/interview-with-dr-byron-hyde-and.html">http://cfstreatment.blogspot.com/2013/01/interview-with-dr-byron-hyde-and.html</a>

 </p>

<blockquote class="messageText SelectQuoteContainer ugc baseHtml" ><b >Testing Info

Comprehensive Stool Analysis PDF</b>

<a href="http://www.gdx.net/core/interpretive-guides/CDSA-Combo-Interp-Guide.pdf" target="_blank" class="externalLink" rel="nofollow" >http://www.gdx.net/core/interpretive-guides/CDSA-Combo-Interp-Guide.pdf</a>

<b>

Clinical Applications of Urinary Organic Acids. Part 2. Dysbiosis Markers </b>

<a href="http://altmedrev.com/publications/13/4/292.pdf" target="_blank" class="externalLink" rel="nofollow" >http://altmedrev.com/publications/13/4/292.pdf</a>

<b>

Hydrogen sulphide in urine test "Neurotoxic metabolite test" and can be ordered online directly from </b><a href="http://www.proteabiopharma.com/page/diagnostics.php" target="_blank" class="externalLink" rel="nofollow" >Protea Biopharma in Belgium</a>.

</blockquote>

</article>

</div>

<div class="editDate" >Last edited: Mar 10, 2014</div>

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<h3 class="userText" ><a href="http://forums.phoenixrising.me/index.php?members/radio.12704/" class="username" dir="auto" itemprop="name" >Radio</a></h3>

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<blockquote class="messageText SelectQuoteContainer ugc baseHtml" ><b >Dysbiosis info

Dysbiosis and Multifocal Dysbiosis: Treatment With Nutritional and Botanical Interventions</b><a href="http://www.naturopathydigest.com/archives/2006/jun/vasquez.php" target="_blank" class="externalLink" rel="nofollow" >http://www.naturopathydigest.com/archives/2006/jun/vasquez.php</a><b>

A Bowel Flora Protocol for Dysbiosis Management</b>

<a href="http://www.mediherb.com/pdf/6041.pdf" target="_blank" class="externalLink" rel="nofollow" >http://www.mediherb.com/pdf/6041.pdf</a>

<b>The gut flora as a forgotten organ</b>

<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500832/" target="_blank" class="externalLink" rel="nofollow" >http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1500832/</a>

<b>Rethinking-Probiotics</b>

<a href="http://forums.phoenixrising.me/index.php?threads/rethinking-probiotics.24643/" class="internalLink" >http://forums.phoenixrising.me/index.php?threads/rethinking-probiotics.24643/</a>

<b>H2S, Fiber and the Gut</b>

<a href="https://groups.google.com/forum/#!topic/sci.life-extension/GVFPy8jiC8E" target="_blank" class="externalLink" rel="nofollow" >https://groups.google.com/forum/#!topic/sci.life-extension/GVFPy8jiC8E</a>

<b>Resistant starch</b>

<a href="http://en.wikipedia.org/wiki/Resistant_starch" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Resistant_starch</a>

<b>The Resistant Starch Challenge</b>

<a href="http://forums.phoenixrising.me/index.php?threads/the-resistant-starch-challenge-is-it-the-key-weve-been-looking-for.26976/" class="internalLink" >http://forums.phoenixrising.me/inde...ge-is-it-the-key-weve-been-looking-for.26976/</a>

<b>Intestinal Dysbiosis PDF <---Good info</b>

<a href="http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&ved=0CCUQFjAA&url=http%3A%2F%2Fwww.becomehealthynow.com%2Fmira2_front%2Fattachment.php%3Fattachmentid%3D57&ei=HFsXU-DqMKONygHXr4DAAw&usg=AFQjCNEGQ3cXY3T5mCddZ9P3lQyi2a_7Hw&sig2=Ui9BTaI-xEAuS9d0KkhsoQ&bvm=bv.62286460,d.aWc" target="_blank" class="externalLink" rel="nofollow" >http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&ved=0CCUQFjAA&url=http://www.becomehealthynow.com/mira2_front/attachment.php?attachmentid=57&ei=HFsXU-DqMKONygHXr4DAAw&usg=AFQjCNEGQ3cXY3T5mCddZ9P3lQyi2a_7Hw&sig2=Ui9BTaI-xEAuS9d0KkhsoQ&bvm=bv.62286460,d.aWc</a>

</blockquote>

</article>

</div>

<div class="editDate" >Last edited: Mar 12, 2014</div>

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<blockquote class="messageText SelectQuoteContainer ugc baseHtml" ><b >7 Causes of Low Stomach Acid- </b>

<b>

Low Stomach Acid Affects On Health </b>

H.Pylori </b>

<b>Dr-Ettingers-Biofilm-Protocol-For-Lyme-and-Gut-Pathogens</b>

<a href="http://www.advancedhealing.com/dr-ettingers-biofilm-protocol-for-lyme-and-gut-pathogens/" target="_blank" class="externalLink" rel="nofollow" >http://www.advancedhealing.com/dr-ettingers-biofilm-protocol-for-lyme-and-gut-pathogens/</a>

<b>

See more about H-pylori info at, </b><a href="http://www.mygutsy.com/is-h-pylori-the-cause-of-allergies-brain-fog-hypothyroid-autoimmune-disorders-adrenal-fatigue/#sthash.1KzwEYym.dpuf" target="_blank" class="externalLink" rel="nofollow" >http://www.mygutsy.com/is-h-pylori-...sorders-adrenal-fatigue/#sthash.1KzwEYym.dpuf</a>

</blockquote>

</article>

</div>

<div class="editDate" >Last edited: Mar 13, 2014</div>

<div class="privateControls" ><a href="http://forums.phoenixrising.me/index.php?members/radio.12704/" class="username author" dir="auto" >Radio</a>, <a href="http://forums.phoenixrising.me/index.php?threads/how-i-recovered-from-cfs-part-2.28684/#post-438853" title="Permalink" class="datePermalink" >Mar 9, 2014</a><a href="http://forums.phoenixrising.me/index.php?posts/438853/report" class="OverlayTrigger item control report" data-cacheoverlay="false" >Report</a><a href="http://forums.phoenixrising.me/index.php?bookmarks/&type=post&id=438853" class="item control bookmarks OverlayTrigger" data-cacheoverlay="false" >Bookmark</a></div>

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<blockquote class="messageText SelectQuoteContainer ugc baseHtml" ><b >Gastritis, Acid Reflux, Helicobacter Pylori, Cholesterol Myth </b>

<b>The high price of antibiotic use: can our guts ever fully recover?</b>

<a href="http://chriskresser.com/the-high-price-of-antibiotic-use-can-our-guts-ever-fully-recover" target="_blank" class="externalLink" rel="nofollow" >http://chriskresser.com/the-high-price-of-antibiotic-use-can-our-guts-ever-fully-recover</a>

</blockquote>

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<div class="editDate" >Last edited: Mar 10, 2014</div>

<div class="privateControls" ><a href="http://forums.phoenixrising.me/index.php?members/radio.12704/" class="username author" dir="auto" >Radio</a>, <a href="http://forums.phoenixrising.me/index.php?threads/how-i-recovered-from-cfs-part-2.28684/#post-438864" title="Permalink" class="datePermalink" >Mar 9, 2014</a><a href="http://forums.phoenixrising.me/index.php?posts/438864/report" class="OverlayTrigger item control report" data-cacheoverlay="false" >Report</a><a href="http://forums.phoenixrising.me/index.php?bookmarks/&type=post&id=438864" class="item control bookmarks OverlayTrigger" data-cacheoverlay="false" >Bookmark</a></div>

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<blockquote class="messageText SelectQuoteContainer ugc baseHtml" ><b >The Silent Liver Damage</b>

H-pylori infection can dramatically reduce stomach acid production. Hydrochloric acid insufficiency could be the main contributing factor to the bacteria over-growth we are seeing. It also could be the underlying cause of the acquired mitochondria damage. I believe we have a genetic factors as well as environmental issues that make us vulnerable to this illness.

The next main issue is the weak liver detoxification and genetic variation genotypes, combined with methylation block and and other chronic deficiencies. The mitochondria can function normally and make all the ATP we need, until a large percentage gets damaged. Now all we needs is a trigger; lyme, viral, mold, toxic exposure or even physical exertion. The elephants in the room are H-pylori, HCL insufficiency, unidentified dysbiosis, and weak liver detoxification. Different organs may get damaged as well in this metabolic dysfunction. The liver damage could be a factor in the hypoglycemia, glycogen storage issues. The hydrochloric acid insufficiency could be related to this silent liver damage.

<b>

The Silent Liver Damage</b>

<a href="http://forums.phoenixrising.me/index.php?threads/monsanto-roundup-the-impacts-of-glyphosate-herbicide-on-human-health-pathways-to-modern-diseases.28937/" class="internalLink" >http://forums.phoenixrising.me/inde...man-health-pathways-to-modern-diseases.28937/</a>

<b>

The Keys To My Recovery </b>

<b>1.</b> Functional Medicine Practitioner (Laboratory Testing / Protocol Support)

<b>2.</b> Modified Paleo Diet + (Glycogen Supportive Foods) + (Beneficial Fermented Substrates)

<b>3.</b> Balance gut organisms (H-pylori / Dysbiosis Support) + (Digestive Aid)

<b>4.</b> Mitochondria Support (Lipid Replacement Therapy) + (CoQ-10 Ubiquinol / Vitamin E Support)

<b>5.</b> Methylation / Mineral Support (Fred Davis' protocol) + (SAMe / Vitamin D Support)

<b>

6. </b>Liver Detoxification / PST Sulfation / Sulfate Support) + (Comprehensive Liver Testing)

<b>7.</b> Spiritual Support

<b>

Limit Vitamin P5P</b> <=== Pyridoxal-5-Phosphate inhibits the PST (phenol sulphur-transferase) activity. P5P is not water soluble and can build up in the body damaging the peripheral nervous system.

<b>The PST sulfation pathway </b>is necessary for the breakdown and removal of certain toxins in the body. This includes the processing of a type of chemical called a phenol. If the Sulfation pathway is not functioning well, a person may not be able to process out the phenolic compounds as fast as they consume them. One of the main reasons for low functioning PST is low sulfate in the body. Sulfate is essential to keep PST functioning. Sulfate is also necessary in maintaing the integrity of the intestinal lining.

<b>Low sulfate levels = increased intestinal permeability (leaky gut).</b>

Low sulfate can occur for a variety of reasons. Some gut infections bacteria / yeast can produce large amounts of phenols, which may overload the PST enzyme.

<b>

Lipid Replacement Therapy</b>

I found the NT Factor® Energy Lipids Powder worked the best for me. (Dose: 1 scoop powder 2-4xday). I like Now foods Super Enzymes for digestive aid support on a empty stomach with the NT Factor support. I supplemented with the lipids for 2 months and recovered soon after combined with the keys to my recovery I have outlined in this thread. I plan on utilizing lipid replacement therapy for the rest of my life.

<b>

Nutricology-Energylipids-Powder-150-Gram</b>

<a href="http://www.amazon.com/Nutricology-Energylipids-Powder-150-Gram/dp/B00908XN20/ref=sr_1_2?ie=UTF8&qid=1394736221&sr=8-2&keywords=NT" target="_blank" class="externalLink" rel="nofollow" >http://www.amazon.com/Nutricology-E...1_2?ie=UTF8&qid=1394736221&sr=8-2&keywords=NT</a> Factor® Energy Lipids Powder

<b>

Tryptophan / NAD+ Deficiency</b>

Viruses and mineral depletion (HCL insufficiency) can also affect the NAD Synthesis. My main concern is the NADH recycling anaerobic metabolism (ADP to ATP) imbalance. This is the reason why it's import to supplement to bypass the depleted NAD+ synthesis. Tryptophan, Nicotinamide, NAD, NADH, R- lipoic acid can help compensate for the NAD+ deficiency.

<b>

Transmethylation</b> is the most important methyl group donor. We need methionine and SAMe to make phospholipids to maintain mitochondrial cell integrity. The <b>HCL insufficiency</b> can also cause intercellular mineral deficiencies. I recommend the toxic urine metals test from Doctor's Data. Also, it is essential that all amalgam fillings be removed by a qualified holistic dentist. <a href="http://www.canarys-eye-view.org/supplements/sammy.html" target="_blank" class="externalLink" rel="nofollow" >http://www.canarys-eye-view.org/supplements/sammy.html</a>

<b>

H-pylori / DysbiosisTreatment Info</b>

<b>

See more about H-pylori info at</b>, <a href="http://www.mygutsy.com/is-h-pylori-the-cause-of-allergies-brain-fog-hypothyroid-autoimmune-disorders-adrenal-fatigue/#sthash.1KzwEYym.dpuf" target="_blank" class="externalLink" rel="nofollow" >http://www.mygutsy.com/is-h-pylori-...sorders-adrenal-fatigue/#sthash.1KzwEYym.dpuf</a>

<b>Dysbiosis and Multifocal Dysbiosis: Treatment With Nutritional and Botanical Interventions</b><a href="http://www.naturopathydigest.com/archives/2006/jun/vasquez.php" target="_blank" class="externalLink" rel="nofollow" >http://www.naturopathydigest.com/archives/2006/jun/vasquez.php</a>

<b>

Key Links 

Alex Vasquez, D.C., N.D.</b><a href="http://www.academia.edu/3862817/Nutritional_and_Botanical_Treatments_Against_Silent_Infections_and_Gastrointestinal_Dysbiosis_Commonly_Overlooked_Causes_of_Neuromusculoskeletal_Inflammation_and_Chronic_Health_Problems" target="_blank" class="externalLink" rel="nofollow" >http://www.academia.edu/3862817/Nut...etal_Inflammation_and_Chronic_Health_Problems</a>

<b>The 4R Gut Healing Program</b>

<a href="http://eastwesthealing.com/the-4r-gut-healing-program/" target="_blank" class="externalLink" rel="nofollow" >http://eastwesthealing.com/the-4r-gut-healing-program/</a>

<b>Reverse-Mitochondrial-Damage-101</b>

<a href="http://forums.phoenixrising.me/index.php?threads/reverse-mitochondrial-damage-101.28175/" class="internalLink" >http://forums.phoenixrising.me/index.php?threads/reverse-mitochondrial-damage-101.28175/</a>

<b>Active B12 therapy and methylation FAQ</b>

<a href="http://howirecovered.com/active-b12-therapy-faq/" target="_blank" class="externalLink" rel="nofollow" >http://howirecovered.com/active-b12-therapy-faq/</a>

<b>Foods high in sulfur (thiols) / <a href="http://perfecthealthdiet.com/the-diet/" target="_blank" class="externalLink" rel="nofollow" >Perfect Health Diet</a></b>

<a href="http://www.livingnetwork.co.za/chelationnetwork/food/high-sulfur-sulphur-food-list/" target="_blank" class="externalLink" rel="nofollow" >http://www.livingnetwork.co.za/chelationnetwork/food/high-sulfur-sulphur-food-list</a>

<b>The low histamine chef diet</b>

<a href="http://thelowhistaminechef.com/" target="_blank" class="externalLink" rel="nofollow" >http://thelowhistaminechef.com/</a>

<b>The PST sulfation pathway</b>

<a href="http://www.blants.com.au/autism.html" target="_blank" class="externalLink" rel="nofollow" >http://www.blants.com.au/autism.html</a>

<b>What You Should Know – Facts About Methylation, Sulfation and Oxidative Stress </b><a href="http://blogs.kirkmanlabs.com/blog/2009/11/10/what-you-should-know-facts-about-methylation-sulfation-and-oxidative-stress/" target="_blank" class="externalLink" rel="nofollow" >http://blogs.kirkmanlabs.com/blog/2...t-methylation-sulfation-and-oxidative-stress/</a>

<b>CFS-and-impaired-sulphur-metabolism</b>

<a href="http://forums.phoenixrising.me/index.php?threads/cfs-and-impaired-sulphur-metabolism.2930/" class="internalLink" >http://forums.phoenixrising.me/index.php?threads/cfs-and-impaired-sulphur-metabolism.2930/</a>

<b>

Multivitamin</b>

I have found a <b>hypoallergenic multivitamin </b>supplement with active B's in a low enough dose that should not cause a problem.<b> Encapsulations, O.N.E Multivitamin </b><a href="http://www.iherb.com/Pure-Encapsula...min-With-Metafolin-L-5-MTHF-60-Capsules/52461%" target="_blank" class="externalLink" rel="nofollow" >http://www.iherb.com/Pure-Encapsula...min-With-Metafolin-L-5-MTHF-60-Capsules/52461%</a>

<aside>

<div class="quote" ><b>How to figure out your Betaine HCL dose</b>

Each person will have a specific supplementary HCL dosage. Unfortunately, there isn’t a special formula I can give you to figure it out. This is a case of trial and error until you get to the correct dosage. Failing to get to your correct dosage can remove the benefits of supplementing.

<b>You must find the right dosage for you situation. If you fail to do the trial and error you’re wasting your time and money. </b>

This is a very common problem we see with our readers. Remember, the stomach is purposely built to handle extreme acid environments. If your correct dosage is 2400mg and you’re only taking 1200mg, you’re not really doing your stomach any favors. You must follow the process below to figure it out the right dosage to get the maximum benefit.

<ol >

<li >Eat a meal that contains at least 15-20grams of protein (about 4-6ounces of meat).</li>

<li >Start by taking 1 pill (650mg of less) of Betaine HCL during the beginning of the meal</li>

<li >Finish the meal as normal and observe your body for any changes in feeling associated with the stomach and belly button area. Things to look for: heaviness, hotness, burning, or other GI distress.</li>

<li >Stay at this dosage of 1 pill for another day of meals with protein and if you don’t notice anything on the 3rd day, try 2 pills.</li>

<li >Stay there for another day and then try 3 pills.</li>

<li >Keep increasing the number of pills taken with each meal until you notice some GI discomfort described in step #3.</li>

<li ><b>When this happens, you will know your ideal Betaine HCL dosage is 1 pill less. </b>For example, if you felt the discomfort going from 5 pills to 6 pills, then 5 pills is your proper dosage for a normal meal.</li>

</ol>

<b>A couple points to clarify:</b>

If you eat a snack or a meal without much protein, you won’t need as much Betaine HCL (for a small snack like a piece of fruit you won’t need any at all)

When you experience the GI discomfort finding your correct dosage, you can mix ½ teaspoon of baking soda in 8oz of water and drink it to help lessen the pain.

Dr. Wright <a href="http://amzn.to/qiLEot" target="_blank" class="externalLink" rel="nofollow" >notes in his book</a> that <i>“paradoxically adverse symptoms are most likely to occur in individuals with the lowest levels of stomach acid. This is because these people are most likely to have atrophic gastritis (a thinned-out stomach lining), which makes them much more sensitive to even small quantities of HCL than a normal, thicker stomach lining.”</i> This makes sense because a super inflamed stomach lining won’t have its normal protective barrier intact to contain the strong acids. In this case, it is wise to start with digestive bitters or get smaller dose Betaine HCL pills (think 350mg or less).

If you have low stomach acid and you can’t supplement with Betaine HCL, there’s a few natural methods to help with symptoms. Start by taking a shot of lemon juice or vinegar before a meal to help the symptoms of indigestion. But know that these don’t actually help the digestion of food only the symptoms. A supplement that can help the digestion is <a href="http://amzn.to/xPInSW" target="_blank" class="externalLink" rel="nofollow" >digestive bitters</a>.

<b>I Need to Take How Many Betaine HCL Pills?</b>

It’s very common for people to stop short of their needed Betaine HCL dosage. In fact, in the beginning I was nervous about taking 6 pills at a meal. But trust me. there is nothing to worry about. <b>Dr. Wright reports that the common Betaine HCL dosage range in his clinical practice is 3,250-4,550mg per meal.</b> That means there are also plenty of people who need above 5,000mg for an effective dosage.

Remember a normal functioning stomach is capable of producing and handling extreme acid ranges. If your dosage starts getting extremely high without any GI distress (step #3), you must use your GI symptoms as a guide instead. These including burping, bloating, farting, and stool consistency. Keep everything else the same in your diet as you wait for these indicators to change for the better. Just because you can take 20 pills, doesn’t mean you should. It could be that at 11 pills all of your problems disappear. For this group of people try to find the minimum dose needed to help your GI symptoms and for peat sakes go get more testing to figure out what is going on!

<b>Best Betaine HCL Supplement brands</b>

When choosing a Betaine HCL supplement it’s important to choose one that includes pepsin. It’s assumed by the medical research that when supplementing with HCL you need to supplement with pepsin. That is why most Betaine HCL supplements you’ll find include it and Dr. Wright recommends it.

I also try to look for a brand that has a minimal amount of additives in the pills. I like the following brands (which are all SCD legal):

See more at: <a href="http://scdlifestyle.com/2012/03/how-to-supplement-with-betaine-hcl-for-low-stomach-acid/" target="_blank" class="externalLink" rel="nofollow" >http://scdlifestyle.com/2012/03/how-to-supplement-with-betaine-hcl-for-low-stomach-acid/</a></div>

</blockquote>

</aside>

</div>

<b>

4 Common Betaine HCl Mistakes</b>

<a href="http://scdlifestyle.com/2013/10/4-common-betaine-hcl-mistakes/" target="_blank" class="externalLink" rel="nofollow" >http://scdlifestyle.com/2013/10/4-common-betaine-hcl-mistakes/</a></blockquote>

</article>

</div>

</li>

</ol>

<aside>

<div class="attribution type" >Aerose91 said: <a href="http://forums.phoenixrising.me/index.php?goto/post&id=439233#post-439233" class="AttributionLink" >↑</a></div>

<div class="quote" >I cant believe no one has commented on this, its a wealth of great info, thank you.

A few diet questions tho- ive always eaten very well but obviously my gut is out of whack. My base food is home made bone broth, himilayan pink salt and home made coconut kefir. How did you figure out which fermented foods to eat, and moreso, how do you know when your gut is healed well enough to take it to the next step? I feel like theres something wrong here that prevents our gut from being able to heal.</div>

</blockquote>

</aside>

</div>

Hey Aerose,

We need to test and treat the core problems first, before the gut can heal and fermented foods can have the most beneficial effect.

1<b>. </b>Eradicate and inhibit H-pylori infection

Dysbiosis Protocol

Hypochlorhydria (HCL insufficiency) Digestive Aid Support

Liver Detoxification Support

<b>

H2S, Fiber and the Gut</b>

<b>Rethinking-Probiotics</b>

<a href="http://forums.phoenixrising.me/index.php?threads/rethinking-probiotics.24643/" class="internalLink" >http://forums.phoenixrising.me/index.php?threads/rethinking-probiotics.24643/</a>

<b>Resistant starch</b>

<a href="http://en.wikipedia.org/wiki/Resistant_starch" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Resistant_starch</a>

<b>The Resistant Starch Challenge</b>

<b>Find A Functional Medicine Practitioner</b>

<a href="https://www.functionalmedicine.org/practitioner_search.aspx?id=117" target="_blank" class="externalLink" rel="nofollow" >https://www.functionalmedicine.org/practitioner_search.aspx?id=117</a>

</blockquote>

</article>

</div>

<div class="editDate" >Last edited: Mar 16, 2014</div>

<div class="privateControls" ><a href="http://forums.phoenixrising.me/index.php?members/radio.12704/" class="username author" dir="auto" >Radio</a>, <a href="http://forums.phoenixrising.me/index.php?threads/how-i-recovered-from-cfs-part-2.28684/#post-439304" title="Permalink" class="datePermalink" >Mar 10, 2014</a><a href="http://forums.phoenixrising.me/index.php?posts/439304/report" class="OverlayTrigger item control report" data-cacheoverlay="false" >Report</a><a href="http://forums.phoenixrising.me/index.php?bookmarks/&type=post&id=439304" class="item control bookmarks OverlayTrigger" data-cacheoverlay="false" >Bookmark</a></div>

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<h3 class="userText" ><a href="http://forums.phoenixrising.me/index.php?members/radio.12704/" class="username" dir="auto" itemprop="name" >Radio</a></h3>

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<blockquote class="messageText SelectQuoteContainer ugc baseHtml" ><b >Dysbiosis Links and Research

Bacterial, Fungal & Parasitic Overgrowth</b>

<a href="http://www.medicalinsider.com/bacterial.html" target="_blank" class="externalLink" rel="nofollow" >http://www.medicalinsider.com/bacterial.html</a><b>

Increased D-Lactic Acid Intestinal Bacteriain Patients with Chronic Fatigue Syndrome</b>

<a href="http://www.cfids-cab.org/rc/Sheedy.pdf" target="_blank" class="externalLink" rel="nofollow" >http://www.cfids-cab.org/rc/Sheedy.pdf</a>

<b>d-Lactate in Human and Ruminant Metabolism </b>

<a href="http://jn.nutrition.org/content/135/7/1619.full" target="_blank" class="externalLink" rel="nofollow" >http://jn.nutrition.org/content/135/7/1619.full</a>

<b>

Hydrogen sulfide theory and gut dysbiosis:</b><a href="http://phoenixrising.me/wp-content/uploads/H2S1.pdf" target="_blank" class="externalLink" rel="nofollow" >http://phoenixrising.me/wp-content/uploads/H2S1.pdf</a>

<b>

Great Book: Fibromyalgia in a Nutshell: A Safe and Effective Functional Medicine Strategy.</b>

A complex condition deciphered based on published (and often overlooked) research—the hope for cure for millions of people who have suffered far too long! Summarizing research presented in Europe in March 2012, "Fibromyalgia in a Nutshell" is an updated excerpt from two of Dr Vasquez's recent books for doctors: "Migraine Headaches, Hypothyroidism, and Fibromyalgia" and "Integrative Orthopedics—Third Edition." This edition of the information has been completely reviewed and revised for easier reading by the general public; doctors and patients alike will find this information clinically accurate as well as therapeutically applicable for daily use.

<b>You can find this book at Amazon.com...</b><img src="/1a4500ba-f722-5276-b3fe-875bffa2bbce.png"/>

<b>Fibromyalgia in a Nutshell: A Safe and Effective Functional Medicine Strategy </b></blockquote>

</article>

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<aside>

<div class="attribution type" >Aerose91 said: <a href="http://forums.phoenixrising.me/index.php?goto/post&id=439679#post-439679" class="AttributionLink" >↑</a></div>

<div class="quote" >What did those treatments involve? I just had a candida test but thats it, if it comes back positive i will start treatment</div>

</blockquote>

</aside>

</div>

xrunner said goldenseal plus cryptolepsis, kib 500, ivermectin (not at the same time) and cat's claw whilst in parallel drinking regularly green tea with honey (pubmed has references on the action of these two on microbes and fungi)</li>

<blockquote class="messageText SelectQuoteContainer ugc baseHtml" >So the past two days ive been upping my HCL to find the correct dosage. im up to 5 pills/meal with no stomach problems or aches yet. However, the past two days my sleep has been terrible- tossing and turning all night, never sleeping more than 20 minutes at a clip, increased psychosis (im ususally flirting with psychosis 24/7 anyway but this dropped me right back into it, especially at night) and much, much increased brain fog. <br />

Can this be a methylation thing? What could cause that? Im going to cut back on the HCL to 2/meal for a couple days though and see if it helps.

</blockquote>

</article>

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<div class="privateControls" ><a href="http://forums.phoenixrising.me/index.php?members/aerose91.12098/" class="username author" dir="auto" >Aerose91</a>, <a href="http://forums.phoenixrising.me/index.php?threads/how-i-recovered-from-cfs-part-2.28684/#post-439989" title="Permalink" class="datePermalink" >Mar 12, 2014</a><a href="http://forums.phoenixrising.me/index.php?posts/439989/report" class="OverlayTrigger item control report" data-cacheoverlay="false" >Report</a><a href="http://forums.phoenixrising.me/index.php?bookmarks/&type=post&id=439989" class="item control bookmarks OverlayTrigger" data-cacheoverlay="false" >Bookmark</a></div>

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<div class="attribution type" >Aerose91 said: <a href="http://forums.phoenixrising.me/index.php?goto/post&id=439989#post-439989" class="AttributionLink" >↑</a></div>

<div class="quote" >So the past two days ive been upping my HCL to find the correct dosage. im up to 5 pills/meal with no stomach problems or aches yet. However, the past two days my sleep has been terrible- tossing and turning all night, never sleeping more than 20 minutes at a clip, increased psychosis (im ususally flirting with psychosis 24/7 anyway but this dropped me right back into it, especially at night) and much, much increased brain fog.

<b>Can this be a methylation thing? </b>What could cause that? Im going to cut back on the HCL to 2/meal for a couple days though and see if it helps.</div>

</blockquote>

</aside>

</div>

Yes, HCL Betaine is a methyl donor. It's possible you could have the COMT +/+ problem?

I feel we need to treat H-pylori / Dysbiosis first and address diet before high dose HCL therapy can have the most therapeutic value.

Also, some people use bitters or lemon juice or even apple cider vinegar for digestive support. If lemon juice is used, it's important to use a drinking straw and to flush the teeth with water.

<aside>

<div class="quote" >Betaine is a metabolite of choline, and is also known as trimethylglycine or TMG. Betaine hcl works by donating methyl (CH3) groups. This nutrient has the ability to convert homocysteine to methionine. Betaine hydrochloride means it is in combination with hydrochloric acid. Intake from foods is estimated at 0.5 to 2 grams a day.

A methyl donor is simply any substance that can transfer a methyl group, a carbon atom attached to three hydrogen atoms, to another substance. Many important biochemical processes rely on methylation, including the metabolism of lipids, neurotransmitters, and DNA. Scientists suspect that adequate methylation of DNA can prevent the expression of harmful genes, such as cancer genes. It’s quite likely that our body’s ability to methylate declines with age, potentially contributing to the aging process, and therefore supplementation is an interesting potential in terms of health benefits.

<a href="http://www.raysahelian.com/betaine.html" target="_blank" class="externalLink" rel="nofollow" >http://www.raysahelian.com/betaine.html</a></div>

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<div class="editDate" >Last edited: Mar 13, 2014</div>

<div class="privateControls" ><a href="http://forums.phoenixrising.me/index.php?members/radio.12704/" class="username author" dir="auto" >Radio</a>, <a href="http://forums.phoenixrising.me/index.php?threads/how-i-recovered-from-cfs-part-2.28684/#post-440195" title="Permalink" class="datePermalink" >Mar 13, 2014</a><a href="http://forums.phoenixrising.me/index.php?posts/440195/report" class="OverlayTrigger item control report" data-cacheoverlay="false" >Report</a><a href="http://forums.phoenixrising.me/index.php?bookmarks/&type=post&id=440195" class="item control bookmarks OverlayTrigger" data-cacheoverlay="false" >Bookmark</a></div>

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<blockquote class="messageText SelectQuoteContainer ugc baseHtml" >Im not sure what the problem may be, ive never had a genetic test but my doctor may do it. <br />

I already do the apple cider vinaegar and lemon juice to aid in digestion, im really not sure what more i can be doing to help dysbiosis since ive been basically on GAPS and paleo for several years now.

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<div class="privateControls" ><a href="http://forums.phoenixrising.me/index.php?members/aerose91.12098/" class="username author" dir="auto" >Aerose91</a>, <a href="http://forums.phoenixrising.me/index.php?threads/how-i-recovered-from-cfs-part-2.28684/#post-440357" title="Permalink" class="datePermalink" >Mar 13, 2014</a><a href="http://forums.phoenixrising.me/index.php?posts/440357/report" class="OverlayTrigger item control report" data-cacheoverlay="false" >Report</a><a href="http://forums.phoenixrising.me/index.php?bookmarks/&type=post&id=440357" class="item control bookmarks OverlayTrigger" data-cacheoverlay="false" >Bookmark</a></div>

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<div class="attribution type" >Aerose91 said: <a href="http://forums.phoenixrising.me/index.php?goto/post&id=440357#post-440357" class="AttributionLink" >↑</a></div>

<div class="quote" >Im not sure what the problem may be, ive never had a genetic test but my doctor may do it.

I already do the apple cider vinaegar and lemon juice to aid in digestion, <b>im really not sure what more i can be doing to help dysbiosis </b>since ive been basically on GAPS and paleo for several years now.</div>

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<b>

Take a look at these protocol....

</b>

<aside>

<div class="quote" ><b>Oregano oil in an emulsified, time-released tablet:</b></div>

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<aside>

<div class="quote" >Botanical oils that are not emulsified do not attain maximal dispersion in the gastrointestinal tract; products that are not time-released might be absorbed before reaching the colon in sufficient concentrations. Emulsified oil of oregano in a time-released tablet is proven effective in the eradication of harmful gastrointestinal microbes, including <i>Blastocystis hominis, Entamoeba hartmanni, and Endolimax nana</i>.18 An <i>in vitro</i> study19 and clinical experience support the use of emulsified oregano against Candida albicans. The common dose is 600 mg per day in divided doses (e.g., 150 mg four times per day) for at least six weeks.</div>

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<b>

Biotics-Research-Emulsified-Oregano-Tablets</b>

<a href="http://www.amazon.com/Biotics-Research-Emulsified-Oregano-Tablets/dp/B00CQ7OQPA/ref=sr_1_2?s=hpc&ie=UTF8&qid=1394738098&sr=1-2&keywords=Biotics+Research+-+ADP+with+Emulsified+Oil+of+Oregano" target="_blank" class="externalLink" rel="nofollow" >http://www.amazon.com/Biotics-Research-Emulsified-Oregano-Tablets/dp/B00CQ7OQPA/ref=sr_1_2?s=hpc&ie=UTF8&qid=1394738098&sr=1-2&keywords=Biotics Research - ADP with Emulsified Oil of Oregano</a></div>

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<blockquote class="messageText SelectQuoteContainer ugc baseHtml" ><b >Why do we need sulfate support?

</b>

<aside>

<div class="quote" ><b>Sulfur, and Sulphate Reducing Bacteria – Another Piece in the Puzzle</b>

One ‘new’ thing I stumbled upon recently is the importance of sulfur and sulphate reducing bacteria. I’d like to share it with you. I hope you find it as interesting as I do.

Sulfur is an essential mineral found primarily in proteins (sulfur containing amino acids like cysteine and taurine; found heavily in animal proteins) and in Alliaceae vegetables - garlic, onions, broccoli, cauliflower, cabbage, Brussels sprouts, and a few others. Sulfur is also found in varying amounts in grains and nuts.

Source - <a href="https://secure.flickr.com/photos/tator82/451998913/sizes/m/in/photostream/" target="_blank" class="externalLink" rel="nofollow" >https://secure.flickr.com/photos/tator82/451998913/sizes/m/in/photostream/</a>

Sulfur is an essential element in:

<ol >

<li >Nerve growth</li>

<li >Neurotransmitter inactivation</li>

<li >Bone & cartilage growth</li>

<li >Mucus production</li>

<li >Detoxification</li>

</ol>

The big three that I’d like to focus on for this article are:

<ol >

<li >Nerves & Neurotransmitters - proper nervous system function</li>

<li >Mucus production - proper gut health & leaky gut</li>

<li >Detoxification - proper elimination of toxic compounds</li>

</ol>

So if you don’t have enough sulfur in your body you can’t do the three things above, and that makes life tough. Why might you not have enough sulfur?

<ol >

<li >Not eating foods that contain sulfur - probably not a problem for most people, but very restricted eaters, like autistic kids who only eat mac & cheese, might run into this</li>

<li >Poor digestion - if you can’t effectively break down and absorb your food you could run into a sulfur deficiency. Of course we would expect to see this in the context of multiple other nutrient deficiencies.</li>

<li >Sulfate reducing bacteria - my focus for this article</li>

</ol>

The problem with gut bacteria

If you’ve read much of my blog you know I’m a huge fan of good gut bacteria. They make health possible, and when they go bad they cause disease. But here’s a new twist.

Bacteria, especially Streptococcus, Enterococcus and Prevotella, can turn sulfur into hydrogen sulfide gas. Hydrogen sulfide gas smells like rotten eggs, is toxic to our nervous systems and our mitochondria.

So if we have a dysbiosis which contains a good deal of sulphate reducing bacteria, we have problems!

<ol >

<li >Deficiency of sulfur which means

<ol >

<li >Our nervous system doesn’t work properly - nerves can’t grow properly and neurotransmitters can’t be effectively broken down and removed meaning the levels of our neurotransmitters will be imbalanced, causing neurologic and behavioral issues.</li>

<li >We can’t produce enough mucus to keep our guts healthy, meaning chronic issues with leaky gut.</li>

<li >We can’t detoxify effectively - making people toxic (a whole host of problems) and chemically sensitive</li>

</ol>

</li>

<li >Excess hydrogen sulfide which is

<ol >

<li >Toxic to our nervous system - double whammy when combined with sulfur deficiency</li>

<li >Toxic to mitochondria - the energy producing parts of our cells. Leading to low energy in our cells and our bodies. Might lead to chronic fatigue like symptoms for some.</li>

</ol>

</li>

</ol>

How do you know if you have this dysbiosis? <b>See more at :

Sulfur, and Sulphate Reducing Bacteria – Another Piece in the Puzzle</b><a href="http://www.aspirenaturalhealth.com/sulfur-and-sulphate-reducing-bacteria-another-piece-in-the-puzzle-post-149-by-dr-tim-gerstmar-3262012/" target="_blank" class="externalLink" rel="nofollow" >http://www.aspirenaturalhealth.com/...e-puzzle-post-149-by-dr-tim-gerstmar-3262012/</a></div>

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<b>Radio: We also need sulfate for wound repair that is required for the extracellular matrix.</b>

<aside>

<div class="quote" ><b>Heparan sulfate analogue: Wound repair</b>

Normal <a href="http://en.wikipedia.org/wiki/Wound_repair" target="blank" class="externalLink" rel="nofollow" >wound repair</a> consists of three different phases: <a href="http://en.wikipedia.org/wiki/Hemostasis" target="blank" class="externalLink" rel="nofollow" >hemostasis</a> and <a href="http://en.wikipedia.org/wiki/Inflammation" target="blank" class="externalLink" rel="nofollow" >inflammation</a>, proliferation and tissue remodeling.<a href="http://en.wikipedia.org/wiki/Heparan_sulfate_analogue#cite_note-Intech-4" target="blank" class="externalLink" rel="nofollow" >[4]</a> In disturbed wound healing, these stages cannot be completed often resulting in a reduced anatomical and functional outcome.<a href="http://en.wikipedia.org/wiki/Heparan_sulfate_analogue#cite_note-Lazarus-13" target="blank" class="externalLink" rel="nofollow" >[13]</a> Multiple factors determine the average healing time of the different phases. These factors can be classified into local factors such as <a href="http://en.wikipedia.org/wiki/Infection" target="blank" class="externalLink" rel="nofollow" >infection</a> and <a href="http://en.wikipedia.org/wiki/Ischemia" target="blank" class="externalLink" rel="nofollow" >ischemia</a>, and systemic factors such as age, stress, <a href="http://en.wikipedia.org/wiki/Diabetes_Mellitus" target="blank" class="externalLink" rel="nofollow" >Diabetes Mellitus</a> and smoking.<a href="http://en.wikipedia.org/wiki/Heparan_sulfate_analogue#cite_note-Guo-14" target="blank" class="externalLink" rel="nofollow" >[14]</a> In chronic wounds, factors as mentioned above, make it impossible for the tissue to regenerate properly.<a href="http://en.wikipedia.org/wiki/Heparan_sulfate_analogue#cite_note-Lazarus-13" target="blank" class="externalLink" rel="nofollow" >[13]</a> After injury, the extracellular matrix, and thereby also the heparan sulfate is broken down by different local <a href="http://en.wikipedia.org/wiki/Enzyme" target="blank" class="externalLink" rel="nofollow" >enzymes</a>, produced by <a href="http://en.wikipedia.org/wiki/Macrophages" target="blank" class="externalLink" rel="nofollow" >macrophages</a> such as, heparanases, serine proteases and <a href="http://en.wikipedia.org/wiki/Metalloproteinase" target="blank" class="externalLink" rel="nofollow" >metalloproteinases</a> (MMPs).<a href="http://en.wikipedia.org/wiki/Heparan_sulfate_analogue#cite_note-Henry-15" target="blank" class="externalLink" rel="nofollow" >[15]</a> Heparan sulfate analogues replace the broken heparan sulfate at the wound site and bind to the free heparan sulfate binding sites of the extracellular matrix. Heparan sulfate is slightly negatively charged and so it can bind the positively charged units of the proteins and secure the ECM scaffold. That ensures a supply of the different protein ligands at the wound site. <b>See more at:</b><a href="http://en.wikipedia.org/wiki/Heparan_sulfate_analogue" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Heparan_sulfate_analogue</a></div>

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<b>

Sulfate Support Supplements

Joint Pain Relief Topical Patch with D-Glucosamine Sulfate and Chondroitin Sulfate Patches</b><a href="http://www.amazon.com/gp/product/B00G4EBZAU/ref=oh_details_o03_s00_i00?ie=UTF8&psc=1" target="_blank" class="externalLink" rel="nofollow" >http://www.amazon.com/gp/product/B00G4EBZAU/ref=oh_details_o03_s00_i00?ie=UTF8&psc=1</a>

<b>

Source Naturals Chondroitin Sulfate 600mg Radio: (I use this as a sublingual)</b>

<a href="http://www.amazon.com/dp/B000GFJJWE/ref=wl_it_dp_o_pC_nS_ttl?encoding=UTF8&colid=STE6K5DNMJYK&coliid=I687Q658W6S8N&psc=1" target="blank" class="externalLink" rel="nofollow" >http://www.amazon.com/dp/B000GFJJWE...colid=STE6K5DNMJYK&coliid=I687Q658W6S8N&psc=1</a>

<b>

Radio: This concludes my broadcast for now <img src="/6550b3c1-813d-5784-8a5e-95ce9bf5b185.png"/> Pay it forward and never give up!

Extracellular matrix</b>

<a href="http://en.wikipedia.org/wiki/Extracellular_matrix" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Extracellular_matrix</a>

<b>

Could Sulfur Deficiency be a Contributing Factor in Obesity, Heart Disease, Alzheimer'sand Chronic Fatigue Syndrome?</b>

<a href="http://people.csail.mit.edu/seneff/sulfur_obesity_alzheimers_muscle_wasting.html" target="_blank" class="externalLink" rel="nofollow" >http://people.csail.mit.edu/seneff/sulfur_obesity_alzheimers_muscle_wasting.html</a>

</blockquote>

</article>

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user ahmo @<a href="http://forums.phoenixrising.me/index.php?members/10670/" class="username" data-user="10670, Cheesus" >Cheesus</a> It's critical to have a detox protocol in place, which include things to bind and to help eliminate the toxins we're releasing. Mercifully, my detoxxing has been going smoothly. I'm happy to detail what I've been using, but you might be more interested in finding a practitioner. After a year of going very slowly, I added frequnt coffee enemas, which has been a great help. I'm linking to a couple resources about coffee enemas. I'm also linking a vid I've just watched from Dr. Dietrich Klinghardt. He'w working w/ autism and Lyme disease. His work suggests Lume is not just tick-borne, but congenital. And he calls such illnesses as MS, Parkinson's, ALS 'adult autism'. He talks about his treatment: Detox; detox; detox; eliminate EMFs. I found this lecture illuminating. Best wishes, ahmo<br />

<br />

<a href="http://www.mygutsy.com/the-ultimate-liver-detox-coffee-enemas/" target="_blank" class="externalLink" rel="nofollow" >http://www.mygutsy.com/the-ultimate-liver-detox-coffee-enemas/</a><br />

<a href="http://www.sawilsons.com/library.htm" target="_blank" class="externalLink" rel="nofollow" >http://www.sawilsons.com/library.htm</a><br />

Klinghardt: Pyroluria, Autism, Lyme <a href="http://www.youtube.com/watch?feature=player_detailpage&v=-z3kRDYcvhA" target="_blank" class="externalLink" rel="nofollow" >http://www.youtube.com/watch?feature=player_detailpage&v=-z3kRDYcvhA</a><br />

Klinghardt. Pyroluria doc: <a href="http://www.klinghardtacademy.com/images/stories/powerpoints/hpu%202009.pdf" target="_blank" class="externalLink" rel="nofollow" >http://www.klinghardtacademy.com/images/stories/powerpoints/hpu 2009.pdf</a></li>

<aside >dx + successful supp for pyroluria 2012; GAPS diet from 1/2012; Freddd's Protocol from 3/2013

++ MAO +/- COMT V158, H62; VDR Bsm, Taq; MTHFR C677, A1298; MTRR H595, A66, K350; BHMT 2,4,8; CBS 699

Freddd's Protocol guide<a href="http://forums.phoenixrising.me/index.php?entries/my-understanding-of-freddds-protocol.1697/" class="internalLink" >1</a>,guide<a href="http://forums.phoenixrising.me/index.php?entries/a-guide-to-freddds-protocol.1618/" class="internalLink" >2</a>, <a href="http://forums.phoenixrising.me/index.php?entries/recent-freddd-posts-on-his-experience-aka-protocol.1742/" class="internalLink" >3</a>, <a href="http://forums.phoenixrising.me/index.php?entries/stepping-into-the-freddd-methylation-protocol.1751/" class="internalLink" >4</a> - Martin <a href="http://www.prohealth.com/library/showarticle.cfm?libid=17947" target="blank" class="externalLink" rel="nofollow" >Pall</a> ,<a href="https://www.youtube.com/watch?v=6A7r1gemjto" target="blank" class="externalLink" rel="nofollow" >video</a> - <a href="http://forums.phoenixrising.me/index.php?entries/my-detox-story-coffee-enemas.1616/" class="internalLink" >Coffee Enemas</a> - <a href="http://ihateticks.wordpress.com/2014/10/06/methylation-for-dummies/" target="_blank" class="externalLink" rel="nofollow" >Methylation for Dummies</a> - <a href="http://forums.phoenixrising.me/index.php?entries/fmn-b2-mao-histamines-oxidative-stress.1772/" class="internalLink" >FMN</a></aside>

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</li>

</ol>

<blockquote class="messageText SelectQuoteContainer ugc baseHtml" >Yes, I think you would benefited from researching lipid replacement therapy and The 7 Key to my Recovery. Also, I would consider doing some comprehensive testing on your kidney function.

</blockquote>

</article>

</div>

</div>

<p>You may have killed off too many of your good bacteria with the oregano. I blame oregano oil for a worsening of my digestive health, after having used it for too long without making an effort to replenish the good bacteria. Still floundering around after that, unfortunately.

Lipds<br />

Myhill's mitochondria supplement package<br />

Chris Kresser's Paleo diet<br />

Infrared sauna (when I am well enough to withstand the heat as I am not currently) <br />

Meditation (improves mitochondrial gene efficiency (and happiness))<br />

The Perrin Technique (lymph drainage to get rid of toxins).

regarding my above list, do you think it might be worth adding NAC in there for detox purposes?</p>

<p>

user Kyzcreig Great write up Radio. I have a similar experience as you - fatigue in my early 20s followed by MCS. Only recently I've made progress with MCS and fatigue (ONOO Pall protocol and Mercury chelation) but I still react to many foods, which precipitates all my other symptoms. I suspect dysbiosis due to liberal antibiotic use was the root cause. Would you say you've cured yourself 100%?</p>

<p>

Edit: I don't have a problem with energy levels per se, at least not since I started using Pall's ONOO protocol. My main problem is with MCS/gut reactions now. Do you think Methylation/B12 deficiency is worth investigating? Are there any diagnostics for it? Curiouslly Freddd's protocol suggests avoiding glutathione - (topical and IV) glutathione seems to be the only thing that cures my ails. That and vitamin C.

 </p>

<aside>

<div class="quote" >There really isn't any evidence that conclusively has proven FM is a progressiv'e mitochondrial disorder' -- do you have evidence of this. There really isn't any evidence that FM can be ameliorated by diet -- please provide studies.

Thanks.</div>

</blockquote>

</aside>

</div>

Hello Kina,

"Progressive mitochondrial disorder" is more of a genetic terminology. I agree with you about FM not being a genetic mitochondria disorder. We are talking about acquired mitochondrial damage from metabolic imbalances related to dysbiosis. There are many other contributing factors such as mercury, viral infections and environmental toxins to consider as well.

Please Review Dr Vasquez's textbooks and peer reviewed biomedical journals. Unfortunately you would need to buy the textbooks see the most of his research.

<aside>

<div class="quote" ><b>A Safe and Effective Functional Medicine Strategy</b>

Authored by Dr Alex Vasquez

A complex condition deciphered based on published (and often overlooked) research-the hope for cure for millions of people who have suffered far too long!

Summarizing research presented in Europe in March 2012, "Fibromyalgia in a Nutshell" is an updated excerpt from two of Dr Vasquez's recent books for doctors: "Migraine Headaches, Hypothyroidism, and Fibromyalgia" and "Integrative Orthopedics-Third Edition." This edition of the information has been completely reviewed and revised for easier reading by the general public; doctors and patients alike will find this information clinically accurate as well as therapeutically applicable for daily use. See more here: <a href="https://www.createspace.com/3838921" target="_blank" class="externalLink" rel="nofollow" >https://www.createspace.com/3838921</a></div>

</blockquote>

</aside>

</div>

<a href="http://www.amazon.com/Fibromyalgia-Nutshell-Effective-Functional-Medicine/dp/1475121253" target="_blank" class="externalLink" rel="nofollow" >http://www.amazon.com/Fibromyalgia-Nutshell-Effective-Functional-Medicine/dp/1475121253</a>

<b>A program consisting of a phytonutrient-rich medical food and an elimination diet ameliorated fibromyalgia symptoms and promoted toxic-element detoxification in a pilot trial.</b><a href="http://www.ncbi.nlm.nih.gov/pubmed/21717823" target="_blank" class="externalLink" rel="nofollow" >http://www.ncbi.nlm.nih.gov/pubmed/21717823</a>

<b>Oxidative stress and mitochondrial dysfunction in fibromyalgia.</b>

<a href="http://www.ncbi.nlm.nih.gov/pubmed/20424583" target="_blank" class="externalLink" rel="nofollow" >http://www.ncbi.nlm.nih.gov/pubmed/20424583</a>

<b>Mitochondrial myopathy presenting as fibromyalgia: a case report</b>

<a href="http://www.jmedicalcasereports.com/content/6/1/55" target="_blank" class="externalLink" rel="nofollow" >http://www.jmedicalcasereports.com/content/6/1/55</a>

<b>Energy Makers Eroding in Fibromyalgia</b>

<a href="http://www.fmnetnews.com/latest-news/energy-makers-eroding-in-fibromyalgia" target="_blank" class="externalLink" rel="nofollow" >http://www.fmnetnews.com/latest-news/energy-makers-eroding-in-fibromyalgia</a>

<b>Vegan diet alleviates fibromyalgia symptoms.</b>

<a href="http://www.ncbi.nlm.nih.gov/pubmed/11093597" target="_blank" class="externalLink" rel="nofollow" >http://www.ncbi.nlm.nih.gov/pubmed/11093597</a>

<b>Relief of fibromyalgia symptoms following discontinuation of dietary excitotoxins.</b>

<a href="http://www.ncbi.nlm.nih.gov/pubmed/11408989" target="_blank" class="externalLink" rel="nofollow" >http://www.ncbi.nlm.nih.gov/pubmed/11408989</a>

<b>Clinical impact of a gluten-free diet on health-related quality of life in seven fibromyalgia syndrome patients with associated celiac disease</b>

<a href="http://www.biomedcentral.com/1471-230X/13/157" target="_blank" class="externalLink" rel="nofollow" >http://www.biomedcentral.com/1471-230X/13/157</a>

<b>The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study.</b>

<a href="http://www.ncbi.nlm.nih.gov/pubmed/17109576" target="_blank" class="externalLink" rel="nofollow" >http://www.ncbi.nlm.nih.gov/pubmed/17109576</a>

<b>Dr Myhill on Fibromyalgia and Mitochondrial Dysfunction</b>

<a href="http://www.prohealth.com/library/showarticle.cfm?libid=16720" target="_blank" class="externalLink" rel="nofollow" >http://www.prohealth.com/library/showarticle.cfm?libid=16720</a>

<b>A link between irritable bowel syndrome and fibromyalgia may be related to findings on lactulose breath testing</b>

<a href="http://ard.bmj.com/content/63/4/450.full" target="_blank" class="externalLink" rel="nofollow" >http://ard.bmj.com/content/63/4/450.full</a>

<b>Fermentation in the gut and CFS</b>

<a href="http://www.drmyhill.co.uk/wiki/Fermentation_in_the_gut_and_CFS" target="_blank" class="externalLink" rel="nofollow" >http://www.drmyhill.co.uk/wiki/Fermentation_in_the_gut_and_CFS</a>

<b>Free radicals, antioxidants and functional foods: Impact on human health</b>

<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249911/" target="_blank" class="externalLink" rel="nofollow" >http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249911/</a>

</blockquote>

</article>

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<div class="editDate" >Last edited: Apr 25, 2014</div>

<ul>

<blockquote class="messageText SelectQuoteContainer ugc baseHtml" ><b >Radio: Dr. Chia has implied that : 

</b>

<aside>

<div class="quote" >"CFS and fibromyalgia are probably the two ends of the same spectrum: one end has much more viruses but little immune response, the other end has few viruses in the tissues but very severe and yet ineffective inflammatory response. <b>I have often seen patients progress from severe CFS to fibromyalgia over several years.</b> See more here "<a href="http://phoenixrising.me/archives/865" target="_blank" class="externalLink" rel="nofollow" >http://phoenixrising.me/archives/865</a></div>

</blockquote>

</aside>

</div>

<aside>

<div class="quote" >Fibromyalgia and ME/CFS: Altered Immune Responses – What I have learned from the use of the immune modulator is dose titration. The needs for patients are usually different depending on the symptoms.

The tolerance issue depends on one’s immune response, the tissue viral load and the organs involved. As we have shown with the cytokine gene expression studies, patient with severe fibromyalia actually did not have quite as bad Th2/Th1 imbalance, as comparing to patients with debilitating fatigue without as much myalgia. Conversely, the viral proteins seen in the stomach biopsy are much more abundant in CFS patients than that in fibromyalgia patients (unpublished data). CFS and fibromyalgia are probably the two ends of the same spectrum: one end has much more viruses but little immune response, the other end has few viruses in the tissues but very severe and yet ineffective inflammatory response. I have often seen patients progress from severe CFS to fibromyalgia over several years.<a href="http://phoenixrising.me/archives/865" target="_blank" class="externalLink" rel="nofollow" >http://phoenixrising.me/archives/865</a>

<b>

Read more: Me and Dr. Chia : A Chronic Fatigue Syndrome Patient Visits Dr. Chia </b><a href="http://www.cortjohnson.org/blog/2013/02/23/me-and-dr-chia-chronic-fatigue-syndrome/" target="_blank" class="externalLink" rel="nofollow" >http://www.cortjohnson.org/blog/2013/02/23/me-and-dr-chia-chronic-fatigue-syndrome/</a>

<b>

Me-and-Dr-Chia-chronic-fatigue-syndrome</b>

<a href="http://www.cortjohnson.org/blog/2013/02/23/me-and-dr-chia-chronic-fatigue-syndrome/" target="_blank" class="externalLink" rel="nofollow" >http://www.cortjohnson.org/blog/2013/02/23/me-and-dr-chia-chronic-fatigue-syndrome/</a></div>

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<b>

Chronic-fatigue-syndrome-fibromyalgia-buzz</b>

<a href="http://www.cortjohnson.org/chronic-fatigue-syndrome-fibromyalgia-buzz/" target="_blank" class="externalLink" rel="nofollow" >http://www.cortjohnson.org/chronic-fatigue-syndrome-fibromyalgia-buzz/</a>

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<div class="editDate" >Last edited: Apr 25, 2014</div>

<div class="privateControls" ><a href="http://forums.phoenixrising.me/index.php?members/radio.12704/" class="username author" dir="auto" >Radio</a>, <a href="http://forums.phoenixrising.me/index.php?threads/how-i-recovered-from-cfs-part-2.28684/page-3#post-456491" title="Permalink" class="datePermalink" >Apr 25, 2014</a><a href="http://forums.phoenixrising.me/index.php?posts/456491/report" class="OverlayTrigger item control report" data-cacheoverlay="false" >Report</a><a href="http://forums.phoenixrising.me/index.php?bookmarks/&type=post&id=456491" class="item control bookmarks OverlayTrigger" data-cacheoverlay="false" >Bookmark</a></div>

</div>

<div class="likesSummary secondaryContent" ><a href="http://forums.phoenixrising.me/index.php?members/maryb.436/" class="username" dir="auto" >maryb</a> likes this.</div>

</div>

</li>

<blockquote class="messageText SelectQuoteContainer ugc baseHtml" ><b >The Vicious Cycle to Recovery (Simplified overview)</b>

I was born with inherited genetic polymorphisms in the methylation cycle as well as slow liver function. This caused my body to produce limited amounts of glutathione, which is needed to protect the body from mercury toxicity.

Mercury toxicity can affect the kidney's ability to recycle sulfates. Sulfates are needed to make mucus and bile acids that protect the body from viruses and other infections. Mucus, Bile acid, and stomach acid insufficiencies can be a contributing factor in acquiring dysbiosis. See more here:<b><a href="http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=0CDIQFjAB&url=http%3A%2F%2Fwww.allnaturaladvantage.com.au%2FSulphation_diagram.htm&ei=PNk6U4zyIaPYyAHOxIHoCA&usg=AFQjCNHQbFoIT29r6aYtF8wndRlkRYryCA&sig2=h8K7PdYYqJfUepxHo6rwQw&bvm=bv.63934634,d.aWc&cad=rja" target="_blank" class="externalLink" rel="nofollow" ><i>Sulphation</i></a></b>

Dysbiosis related toxins can silently damage the mitochondria as well as many other areas of the body. These related toxins can overload the liver and accelerate viral inflammation.

The key to my recovery was addressing all these contributing factors and focusing on slowing down the progression of my illness. I also needed to address the viral aspect in order to control the immune system's inflammatory response. I found that reducing viral inflammation and improve blood flow was the key factor in controlling my pain. I am now researching how virus can injury the calcium channels and contribute to this vicious cycle.

<b>Radio:</b> Can the channelopathy theory be related to Dr. Chia work?

<aside>

<div class="quote" >AbstractIt is suggested that chronic fatigue syndrome/fibromyalgia is caused by virus injury to the calcium channels leading to larger quantities than usual of calcium ions entering the striated muscle cells. Should this be true, then treatment with a calcium antagonist (CA) may possibly be of value.<a href="http://www.mecfsforums.com/index.php?topic=6230.0" target="_blank" class="externalLink" rel="nofollow" >http://www.mecfsforums.com/index.php?topic=6230.0</a></div>

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<b>

A Neurological Channelopathy in Chronic Fatigue Syndrome (ME/CFS)? </b><a href="http://phoenixrising.me/research-2/the-brain-in-chronic-fatigue-syndrome-mecfs/a-neurological-channelopathy-in-chronic-fatigue-syndrome-mecfs" target="_blank" class="externalLink" rel="nofollow" >http://phoenixrising.me/research-2/...annelopathy-in-chronic-fatigue-syndrome-mecfs</a>

<b>Effect of coxsackievirus b3 on ion channel currents in rat ventricular myocytes</b>.<a href="http://www.ncbi.nlm.nih.gov/pubmed/12903773" target="_blank" class="externalLink" rel="nofollow" >http://www.ncbi.nlm.nih.gov/pubmed/12903773</a>

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<li id="post-456503" class="message " data-author="Radio" >Please refer to Dr. Chia protocols on how to address viruses. Also, forum member<b><a href="http://forums.phoenixrising.me/index.php?members/hip.249/" class="internalLink" > Hip@</a></b> has post some great info on this topic.</li>

<li id="post-456503" class="message " data-author="Radio" >Have you tried a topical glutathione supplement? I'm using both S-Acetyl-Glutathione and a topical cream and find they dramatically reduce my symptoms. The regular reduced glutathione oral supplements do nothing for me however. Frankly, I'm not sure about SAG yet but I'm going to keep taking it until I run out. The cream is noticeably effective.<br />

<br />

It's worth noting mercury competes with and edges out selenium which is crucial for the enzymes which reduce and recycle glutathione. This can create a vicious cycle whereby dysbiosis depletes glutathione, which is how the body deals with mercury, and then leads to an accumulation of mercury which itself encourages dysbiosis. I had severe mercury toxicity whose origin I never understood (I never had amalgams). Knowing what I know now I could postulate it was from a long standing dysbiosis which led to an accumulation of mercury from diet (I used to eat a lot of seafood) and ultimately a more severe dysbiosis and manifestation of symptoms.<br />

<br />

Here's a write up on glutathione recycling and what you can do about it:<br />

<a href="http://thyroidbook.com/blog/glutathione-recycling-for-autoimmune-disease/" target="_blank" class="externalLink" rel="nofollow" >http://thyroidbook.com/blog/glutathione-recycling-for-autoimmune-disease/</a><br />

Here's one about leaky gut specifically.<br />

<a href="http://sanjosefuncmed.com/intestinal-permeability-clinical-unwinding-leaky-gut/" target="_blank" class="externalLink" rel="nofollow" >http://sanjosefuncmed.com/intestinal-permeability-clinical-unwinding-leaky-gut/</a><br />

At least in my case simply eliminating foods and taking antimicrobials hasn't cured my gut symptoms, so I plan to follow this protocol next.<br />

<br />

The following is a comprehensive supplement for glutathione recycling: <a href="http://www.naturalhealthyconcepts.com/glutathione-recycler-K57-90-p-apex-energetics.html" target="_blank" class="externalLink" rel="nofollow" >http://www.naturalhealthyconcepts.com/glutathione-recycler-K57-90-p-apex-energetics.html</a><br />

I'm planning on taking each component individually however and seeing what I have success with.</li>

<blockquote class="messageText SelectQuoteContainer ugc baseHtml" >, hydrogen sulphide can inhibit mitochondrial function relating to sulfate-reducing bacteria as well as many other gut toxins. I think mitochondrial function is absolutely related to gut dysfunction. I'm not saying this is the only contributing factor as viral inflammation could big player as well.

Also, high dose lipid replacement therapy was the critical factor in my recovery.

<aside>

<div class="quote" >Work done by Professor Kenny De Meirleir(2) has shown that <a href="http://www.ei-resource.org/articles/chronic-fatigue-syndrome-articles/gut-bacteria,-the-h2s-test-%26-mitochondrial-dysfunction-in-me%10cfs/#" target="_blank" class="externalLink" rel="nofollow" >people with chronic fatigue syndrome</a> consistently have higher levels of hydrogen sulfide in their urine compared to normal controls. Furthermore, this is associated with high levels of bacteria which are not normally found in the gut flora. See more here:

<b>Gut Bacteria, the H2S Test & Mitochondrial Dysfunction in ME/CFS </b>

<a href="http://www.ei-resource.org/articles/chronic-fatigue-syndrome-articles/gut-bacteria,-the-h2s-test-%26-mitochondrial-dysfunction-in-me%10cfs/" target="_blank" class="externalLink" rel="nofollow" >http://www.ei-resource.org/articles/chronic-fatigue-syndrome-articles/gut-bacteria,-the-h2s-test-&-mitochondrial-dysfunction-in-mecfs/</a></div>

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<div class="quote" >The <a href="http://en.wikipedia.org/wiki/Enzyme" target="blank" class="externalLink" rel="nofollow" >enzyme</a> <b>cytochrome c oxidase</b> or <b>Complex IV</b>, <a href="http://en.wikipedia.org/wiki/Enzyme_Commission_number" target="blank" class="externalLink" rel="nofollow" >EC</a> <a href="http://enzyme.expasy.org/EC/1.9.3.1" target="blank" class="externalLink" rel="nofollow" >1.9.3.1</a>) is a large <a href="http://en.wikipedia.org/wiki/Transmembrane_protein" target="blank" class="externalLink" rel="nofollow" >transmembrane protein</a> complex found in <a href="http://en.wikipedia.org/wiki/Bacteria" target="blank" class="externalLink" rel="nofollow" >bacteria</a> and the <a href="http://en.wikipedia.org/wiki/Mitochondrion" target="blank" class="externalLink" rel="nofollow" >mitochondrion</a> of <a href="http://en.wikipedia.org/wiki/Eukaryotes" target="_blank" class="externalLink" rel="nofollow" >eukaryotes</a>.

It is the last enzyme in the respiratory <a href="http://en.wikipedia.org/wiki/Electron_transport_chain" target="blank" class="externalLink" rel="nofollow" >electron transport chain</a> of mitochondria (or bacteria) located in the mitochondrial (or bacterial) membrane. It receives an electron from each of four <a href="http://en.wikipedia.org/wiki/Cytochrome_c" target="blank" class="externalLink" rel="nofollow" >cytochrome c</a> molecules, and transfers them to one oxygen molecule, converting molecular <a href="http://en.wikipedia.org/wiki/Oxygen" target="blank" class="externalLink" rel="nofollow" >oxygen</a> to two molecules of water. In the process, it binds four protons from the inner aqueous phase to make water, and in addition translocates four protons across the membrane, helping to establish a transmembrane difference of proton <a href="http://en.wikipedia.org/wiki/Electrochemical_potential" target="blank" class="externalLink" rel="nofollow" >electrochemical potential</a> that the <a href="http://en.wikipedia.org/wiki/ATP_synthase" target="blank" class="externalLink" rel="nofollow" >ATP synthase</a> then uses to synthesize <a href="http://en.wikipedia.org/wiki/Adenosine_triphosphate" target="blank" class="externalLink" rel="nofollow" >ATP</a>. see more here: <a href="http://en.wikipedia.org/wiki/Cytochrome_c_oxidase" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Cytochrome_c_oxidase</a></div>

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<div class="quote" ><a href="http://en.wikipedia.org/wiki/Cyanide" target="blank" class="externalLink" rel="nofollow" >Cyanide</a>, <b><a href="http://en.wikipedia.org/wiki/Hydrogen_sulfide" target="blank" class="externalLink" rel="nofollow" >sulfide</a></b>, <a href="http://en.wikipedia.org/wiki/Azide" target="blank" class="externalLink" rel="nofollow" >azide</a>, and <a href="http://en.wikipedia.org/wiki/Carbon_monoxide" target="blank" class="externalLink" rel="nofollow" >carbon monoxide</a><a href="http://en.wikipedia.org/wiki/Cytochrome_c_oxidase#cite_note-pmid12969439-6" target="blank" class="externalLink" rel="nofollow" >[6]</a> all bind to cytochrome c oxidase, thus <a href="http://en.wikipedia.org/wiki/Competitive_inhibition" target="blank" class="externalLink" rel="nofollow" >competitively</a> inhibiting the protein from functioning, which results in chemical <a href="http://en.wikipedia.org/wiki/Asphyxiation" target="blank" class="externalLink" rel="nofollow" >asphyxiation</a> of cells. <a href="http://en.wikipedia.org/wiki/Methanol" target="blank" class="externalLink" rel="nofollow" >Methanol</a> in <a href="http://en.wikipedia.org/wiki/Denatured_alcohol" target="blank" class="externalLink" rel="nofollow" >methylated spirits</a> is converted into <a href="http://en.wikipedia.org/wiki/Formic_acid" target="blank" class="externalLink" rel="nofollow" >formic acid</a>, which also inhibits the same oxidase system. See more here: <a href="http://en.wikipedia.org/wiki/Cytochrome_c_oxidase" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Cytochrome_c_oxidase</a></div>

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<b>

Fermentation in the gut and CFS</b>

<a href="http://www.drmyhill.co.uk/wiki/Fermentation_in_the_gut_and_CFS" target="_blank" class="externalLink" rel="nofollow" >http://www.drmyhill.co.uk/wiki/Fermentation_in_the_gut_and_CFS</a>

<b>The De Meirleir Experience</b>

<a href="http://forums.phoenixrising.me/index.php?threads/the-de-meirleir-experience.21586/" class="internalLink" >http://forums.phoenixrising.me/index.php?threads/the-de-meirleir-experience.21586/</a>

<b>Gut inflammation in chronic fatigue syndrome</b>

<a href="http://www.nutritionandmetabolism.com/content/7/1/79" target="_blank" class="externalLink" rel="nofollow" >http://www.nutritionandmetabolism.com/content/7/1/79</a>

<b>International ME/CFS clinicians and researchers</b>

<a href="http://www.mecfs-vic.org.au/international-mecfs-clinicians-and-researchers" target="_blank" class="externalLink" rel="nofollow" >http://www.mecfs-vic.org.au/international-mecfs-clinicians-and-researchers</a>

<b>Nicolson 2014 - Use of Natural Supplements to Improve Mitochondrial Function (CFS)</b><a href="http://forums.phoenixrising.me/inde...-to-improve-mitochondrial-function-cfs.28103/" class="internalLink" >http://forums.phoenixrising.me/inde...-to-improve-mitochondrial-function-cfs.28103/</a>

<b>Read more: Me and Dr. Chia : A Chronic Fatigue Syndrome Patient Visits Dr. Chia </b><a href="http://www.cortjohnson.org/blog/2013/02/23/me-and-dr-chia-chronic-fatigue-syndrome/" target="_blank" class="externalLink" rel="nofollow" >http://www.cortjohnson.org/blog/2013/02/23/me-and-dr-chia-chronic-fatigue-syndrome/</a>

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<div class="attribution type" >maryb said: <a href="http://forums.phoenixrising.me/index.php?goto/post&id=456560#post-456560" class="AttributionLink" >↑</a></div>

<div class="quote" >@<a href="http://forums.phoenixrising.me/index.php?members/12704/" class="username" data-user="12704, Radio" >Radio</a>

" I <b>was born with inherited genetic polymorphisms in the methylation cycle as well as slow liver function. This caused my body to produce limited amounts of glutathione, which is needed to protect the body from mercury toxicity.

Mercury toxicity can affect the kidney's ability to recycle sulfates. Sulfates are needed to make mucus and bile acids that protect the body from viruses and other infections. Mucus, Bile acid, and stomach acid insufficiencies can be a contributing factor in acquiring dysbiosis. See more here:</b><a href="http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=0CDIQFjAB&url=http%3A%2F%2Fwww.allnaturaladvantage.com.au%2FSulphation_diagram.htm&ei=PNk6U4zyIaPYyAHOxIHoCA&usg=AFQjCNHQbFoIT29r6aYtF8wndRlkRYryCA&sig2=h8K7PdYYqJfUepxHo6rwQw&bvm=bv.63934634,d.aWc&cad=rja" target="_blank" class="externalLink" rel="nofollow" ><i><b>Sulphation</b></i></a>

<b>3. Dysbiosis related toxins can silently damage the mitochondria as well as many other areas of the body. These related toxins can overload the liver and accelerate viral inflammation."</b>

I've found this particularly interesting as I've crashed badly over the past 4 months - it started exactly 3 weeks after having an amalgam filling out, the last one I had out 3 years ago caused the same reaction. I was better at the time though and seemed to come out of it after about 4 months, this time not so. My recent vit/mineral result from spectracell showed very low glutathione, advice - supplement. no no - tried that, also IV - not a good response.

I've recently tried starting a herbal a/viral/bacterial product (Samento) but the reactions were too overwhelming for me. So from this it seems I need to address the mercury before anything else, difficult as I still have 2 amalgams left in. I would definitely go for IV chelation if I was amalgam free. Another thing the useless UK government is responsible for, dentists are still using these fillings on the poor/and those unaware of the dangers.</div>

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<p><b >There are many possible contributing factors </b>that can overwhelm the body's metabolism such ; lyme disease, viruses, non-cytolytic viruses, mold, toxic exposure as well as dysbiosis, endotoxins and even physical exertion can all dramatically affect the liver's detoxification process. Chronic viral infections and mercury toxicity have been associated with chronic inflammation of the liver and kidneys, further inhibiting PST enzyme as well as sulfate recycling. See more here: <a href="http://healthyawareness.com/thread-phenol-sulfotransferase-pst-and-the-feingold-diet" target="_blank" class="externalLink" rel="nofollow" >http://healthyawareness.com/thread-phenol-sulfotransferase-pst-and-the-feingold-diet</a><br />

<br />

<b >Sulfate recycling</b> in the kidneys can possibility be blocked by mercury which can accumulate if glutathione is depletion. Sulfate has several important jobs that including sulfating DHEA and toxins including phenols from many foods. There is also the NaSi-1 gene that can possibility be inhibited by mercury and contribute to the faulty sulphate transporter proteins. Sulfate-reducing bacteria in the gut can also be a problem as it is needed to convert sulfate to hydrogen sulfide, which is toxic at high enough levels. Sulfate is also required for mucus / bile acid production need for many protective functions in the body. These insufficiencies can be a contributing factor in acquiring dysbiosis. Bacteria and yeast overgrowth can also produce hydrogen sulfide (H2S) that can bind to the mitochondrial enzyme cytochrome c oxidase, part of the electron transport chain in the krebs cycle. This can also impair oxidative phosphorylation and ATP production. When mitochondria become damaged due to a buildup of toxins, energy production is greatly impaired. Ultimately the mitochondria pays the price for the livers weak detoxification ability.<br />

<br />

<b >Sulfate Versus Sulfur Reducing Bacteria</b><br />

<a href="http://forums.phoenixrising.me/index.php?threads/sulfate-versus-sulfur-reducing-bacteria.6473/" class="internalLink" >http://forums.phoenixrising.me/index.php?threads/sulfate-versus-sulfur-reducing-bacteria.6473/</a><br />

<b >Molecular aspects of renal tubular handling and regulation of inorganic sulfate</b> <img src="/e2d1a25e-a23f-555d-bcf4-03a6ff4c5ff8.png"/><br />

<a href="http://www.nature.com/ki/journal/v59/n3/full/4492098a.html" target="_blank" class="externalLink" rel="nofollow" >http://www.nature.com/ki/journal/v59/n3/full/4492098a.html</a><br />

<b >Renal Na-Si cotransporter NaSi-1 is inhibited by heavy metals.</b><br />

<a href="http://www.ncbi.nlm.nih.gov/pubmed/9486223">http://www.ncbi.nlm.nih.gov/pubmed/9486223</a></p>

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<div class="attribution type" >boohealth said: <a href="http://forums.phoenixrising.me/index.php?goto/post&id=456783#post-456783" class="AttributionLink" >↑</a></div>

<div class="quote" >@<a href="http://forums.phoenixrising.me/index.php?members/14242/" class="username" data-user="14242, kyzcreig" >kyzcreig</a> what creams are you using (percentage, carrier, any URL or weblink)? Thanks</div>

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I was using Kirkman for a while until I found the slightly cheaper Swanson product.

<a href="http://www.amazon.com/L-Glutathione-Cream-Setria-59/dp/B0091QY1OU" target="_blank" class="externalLink" rel="nofollow" >http://www.amazon.com/L-Glutathione-Cream-Setria-59/dp/B0091QY1OU</a>

<a href="http://www.amazon.com/Reduced-L-Glutathione-Lotion-2-oz/dp/B004PLTCVS/ref=sr_1_1?ie=UTF8&qid=1398557312&sr=8-1&keywords=kirkman+glutathione" target="_blank" class="externalLink" rel="nofollow" >http://www.amazon.com/Reduced-L-Glutathione-Lotion-2-oz/dp/B004PLTCVS/ref=sr_1_1?ie=UTF8&qid=1398557312&sr=8-1&keywords=kirkman glutathione</a>

Kirkman might be a bit more effective but not much more enough to justify the cost.

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<blockquote class="messageText SelectQuoteContainer ugc baseHtml" ><b>The question I am asking is </b>sulfate deficiency a factor and can mercury and other heavy metals inhibit NaSi-1gene contribute to a sulphate transporter proteins deficiency needed for sulfate recycling? This is one of many possible contributing factors that can be related to sulfate deficiency.

<b>Renal Na-Sicotransporter NaSi-1is inhibited by heavy metals</b>

<a href="http://ajprenal.physiology.org/content/ajprenal/274/2/F283.full.pdf" target="_blank" class="externalLink" rel="nofollow" >http://ajprenal.physiology.org/content/ajprenal/274/2/F283.full.pdf</a>

<b>

Radio:</b> "We need to challenge ourselves and ask the right questions in order to have full understanding of the root cause of disease."

<aside>

<div class="quote" ><b>Richvank said:</b> <a href="http://forums.phoenixrising.me/index.php?goto/post&id=156477#post-156477" class="internalLink" >↑http://forums.phoenixrising.me/index.php?threads/getting-worse-from-imunovir.8107/page-5</a>

Hi, gu3vara.

Some people with ME/CFS are low in sulfate. This is also true in autism, as published originally by Rosemary Waring. In both these disorders, there is a partial block in methionine sythase in the methylation cycle, and this causes too much of the homocysteine to be lost from the methylation cycle and instead to enter the transsulfuration cycle and pass through sulfoxidation to make sulfate, which then is excreted in the urine. The sulfate transporters in the kidneys can be blocked by mercury or other toxic metals, which build up because of glutathione depletion, and thus not enough sulfate is retained to do several important jobs, including sulfating DHEA, sulfating a range of toxins as part of Phase II detoxication, including phenols from certain foods, and supporting the cartilage in the joints. Some people take Epsom salt baths to raise their sulfate. Most can tolerate them, but a few can't. I suspect that these people have sulfate-reducing bacteria in their gut that convert sulfate to hydrogen sulfide, which is toxic at high enough levels. Fixing the methylation cycle block is the longer range solution to the sulfate deficiency problem.

Best regards,

Rich</div>

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<b>

Chronic fatigue syndrome, Fibromyalgia, Scleroderma, Lupus, Rheumatoid Arthritis, MCS: the mercury connection?</b>

<a href="http://www.flcv.com/cfsfm.html" target="_blank" class="externalLink" rel="nofollow" >http://www.flcv.com/cfsfm.html</a><b>

Rosemary Waring</b>

<a href="http://en.wikipedia.org/wiki/Rosemary_Waring" target="_blank" class="externalLink" rel="nofollow" >http://en.wikipedia.org/wiki/Rosemary_Waring</a>

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<div class="editDate" >Last edited: Apr 27, 2014</div>

<div class="privateControls" ><a href="http://forums.phoenixrising.me/index.php?members/radio.12704/" class="username author" dir="auto" >Radio</a>, <a href="http://forums.phoenixrising.me/index.php?threads/how-i-recovered-from-cfs-part-2.28684/page-3#post-456950" title="Permalink" class="datePermalink" >Apr 27, 2014</a><a href="http://forums.phoenixrising.me/index.php?posts/456950/report" class="OverlayTrigger item control report" data-cacheoverlay="false" >Report</a><a href="http://forums.phoenixrising.me/index.php?bookmarks/&type=post&id=456950" class="item control bookmarks OverlayTrigger" data-cacheoverlay="false" >Bookmark</a></div>

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<h3 class="userText" ><a href="http://forums.phoenixrising.me/index.php?members/radio.12704/" class="username" dir="auto" itemprop="name" >Radio</a></h3>

<dt >Messages:</dt>

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<dt >Likes:</dt>

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<div class="quote" ><b >Kina@ said: There really isn't any evidence that FM can be ameliorated by diet --</b></div>

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The food we eat can have a dramatic impact on many chronic illnesses in general. Diet is a hug factor in my recovery protocol. If our PST Phase II detoxification pathway is not working, I found that diet can really help control the inflammatory response cause by this "possible" dysfunctional metabolism. I really like this approach to healing the body. Please read this thread and the information about free radicals, antioxidants and functional foods.

<b>Free radicals, antioxidants and functional foods: Impact on human health</b>

<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249911/" target="_blank" class="externalLink" rel="nofollow" >http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249911/</a>

<b>CFS and impaired sulphur metabolism</b> <a href="http://forums.phoenixrising.me/index.php?threads/cfs-and-impaired-sulphur-metabolism.2930/" class="internalLink" >http://forums.phoenixrising.me/index.php?threads/cfs-and-impaired-sulphur-metabolism.2930/</a>

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<div class="quote" ><b><a href="http://forums.phoenixrising.me/index.php?members/martial.13018/" class="internalLink" >Martial</a></b>@

I think its important to address the multi level issues that come with chronic illness and find Radio does it perfectly. I have also seen some other response citing that he did not have CFS or that it seems to not benefit for some others. In this case it is important that we look into all possibilities for disease. Radio discusses dysbiosis and mito dysfunction however there are issues for methylation mutations that could be looked into, chronic infections that are hard to catch like Lyme and Co, Parasitic, Viral loads, etc.. Then you have the inflammatory immune response markers that need to be brought into check, deficiencies of vitamins and minerals which can be incredibly taxing on the body and cause all kinds of vicious dysfunctions as well. Toxicities, allergens, heavy metals, etc..

Keep in mind as well that as long as a chronic infection is present there will be dysfunction until it is brought under control.. You could be making all the corrections in the world but as long as it is not dealt with there can't be full recovery even with everything else in place, this is because it will block those enzymes, vitamins, minerals, and physiological functions from its normal functions and homeostasis of the body. There are many, many components in chronic disease so the search for a single underlying cause may not show the same source of trigger into disease for everyone, and is not the only thing to be addressed. Though I think finding a source of dysfunction in the first place is extraordinarily useful and as of now I have huge suspect of methylation issues that make one pre disposed.</div>

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