Genentech

<a href="http://">http://en.wikipedia.org/wiki/Genentech</a><div>
</div><div></div><div><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);"><b>Genentech Inc.</b>, is a <a href="http://en.wikipedia.org/wiki/Biotechnology" title="Biotechnology" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">biotechnology</a> <a href="http://en.wikipedia.org/wiki/Corporation" title="Corporation" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">corporation</a> which became a <a href="http://en.wikipedia.org/wiki/Subsidiary" title="Subsidiary" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">subsidiary</a> of <a href="http://en.wikipedia.org/wiki/Hoffmann%E2%80%93La_Roche" title="Hoffmann–La Roche" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Roche</a> in 2009. Genentech Research and Early Development operates as an independent center within Roche.<sup id="cite_ref-1" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-1" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[1]</a></sup></p><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);">As of November 2014, Genentech employed nearly 12,900 people.<sup id="cite_ref-2" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-2" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[2]</a></sup> In July 2014, Genentech announced its acquisition of <a href="http://en.wikipedia.org/w/index.php?title=Seragon&action=edit&redlink=1" class="new" title="Seragon (page does not exist)" style="text-decoration: none; color: rgb(165, 88, 88); background: none;">Seragon</a> for up to $1.725 billion.<sup id="cite_ref-3" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-3" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[3]</a></sup></p><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);" /><div id="toc" class="toc" style="border: 1px solid rgb(170, 170, 170); padding: 7px; font-size: 13.3000001907349px; display: table; zoom: 1; color: rgb(37, 37, 37); background-color: rgb(249, 249, 249);"><div id="toctitle" style="direction: ltr; text-align: center;"><h2 style="color: black; margin: 1em 0px 0.25em; overflow: hidden; padding: 0px; border: none; font-size: 13.3000001907349px; display: inline; line-height: 1.3; background: none;">Contents</h2> <span class="toctoggle" style="-webkit-user-select: none; font-size: 12.5020008087158px;"> [<a href="http://en.wikipedia.org/wiki/Genentech#" id="togglelink" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">hide</a>] </span></div><ul style="line-height: 1.6; list-style-type: none; margin: 0.3em 0px; padding: 0px; list-style-image: none;"><li class="toclevel-1 tocsection-1" style="margin-bottom: 0.1em;"><a href="http://en.wikipedia.org/wiki/Genentech#History" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span class="tocnumber">1</span> <span class="toctext">History</span></a></li><li class="toclevel-1 tocsection-2" style="margin-bottom: 0.1em;"><a href="http://en.wikipedia.org/wiki/Genentech#Research" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span class="tocnumber">2</span> <span class="toctext">Research</span></a></li><li class="toclevel-1 tocsection-3" style="margin-bottom: 0.1em;"><a href="http://en.wikipedia.org/wiki/Genentech#Facilities" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span class="tocnumber">3</span> <span class="toctext">Facilities</span></a></li><li class="toclevel-1 tocsection-4" style="margin-bottom: 0.1em;"><a href="http://en.wikipedia.org/wiki/Genentech#Controversy" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span class="tocnumber">4</span> <span class="toctext">Controversy</span></a><ul style="line-height: 1.6; list-style-type: none; margin: 0px 0px 0px 2em; padding: 0px; list-style-image: none;"><li class="toclevel-2 tocsection-5" style="margin-bottom: 0.1em;"><a href="http://en.wikipedia.org/wiki/Genentech#Disputes" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span class="tocnumber">4.1</span> <span class="toctext">Disputes</span></a></li></ul></li><li class="toclevel-1 tocsection-6" style="margin-bottom: 0.1em;"><a href="http://en.wikipedia.org/wiki/Genentech#Products_timeline" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span class="tocnumber">5</span> <span class="toctext">Products timeline</span></a></li><li class="toclevel-1 tocsection-7" style="margin-bottom: 0.1em;"><a href="http://en.wikipedia.org/wiki/Genentech#Awards_and_recognitions" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span class="tocnumber">6</span> <span class="toctext">Awards and recognitions</span></a></li><li class="toclevel-1 tocsection-8" style="margin-bottom: 0.1em;"><a href="http://en.wikipedia.org/wiki/Genentech#References" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span class="tocnumber">7</span> <span class="toctext">References</span></a></li><li class="toclevel-1 tocsection-9" style="margin-bottom: 0.1em;"><a href="http://en.wikipedia.org/wiki/Genentech#Further_reading" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span class="tocnumber">8</span> <span class="toctext">Further reading</span></a></li><li class="toclevel-1 tocsection-10" style="margin-bottom: 0.1em;"><a href="http://en.wikipedia.org/wiki/Genentech#External_links" style="text-decoration: none; color: rgb(11, 0, 128); background: none;"><span class="tocnumber">9</span> <span class="toctext">External links</span></a></li></ul></div><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);" /><h2 style="font-weight: normal; margin: 1em 0px 0.25em; overflow: hidden; padding: 0px; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(170, 170, 170); font-family: 'Linux Libertine', Georgia, Times, serif; line-height: 1.3; background: none rgb(255, 255, 255);"><span class="mw-headline" id="History">History</span><span class="mw-editsection" style="-webkit-user-select: none; font-size: small; margin-left: 1em; vertical-align: baseline; line-height: 1em; display: inline-block; white-space: nowrap; unicode-bidi: -webkit-isolate; font-family: sans-serif;"><span class="mw-editsection-bracket" style="margin-right: 0px; color: rgb(85, 85, 85); margin-left: 0px;">[</span><a href="http://en.wikipedia.org/w/index.php?title=Genentech&action=edit&section=1" title="Edit section: History" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">edit</a><span class="mw-editsection-bracket" style="margin-left: 0px; color: rgb(85, 85, 85); margin-right: 0px;">]</span></span></h2><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);">The company was founded in 1976 by venture capitalist <a href="http://en.wikipedia.org/wiki/Robert_A.Swanson" title="Robert A. Swanson" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Robert A. Swanson</a> and biochemist <a href="http://en.wikipedia.org/wiki/Herbert_Boyer" title="Herbert Boyer" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Herbert Boyer</a>.<sup id="cite_ref-Nature2003_01_23_4-0" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-Nature2003_01_23-4" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[4]</a></sup><sup id="cite_ref-Genentech_CorporateOverview_5-0" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-Genentech_CorporateOverview-5" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[5]</a></sup> Boyer is considered to be a pioneer in the field of<a href="http://en.wikipedia.org/wiki/Recombinant_DNA" title="Recombinant DNA" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">recombinant DNA</a> technology. In 1973, Boyer and his colleague <a href="http://en.wikipedia.org/wiki/Stanley_Norman_Cohen" title="Stanley Norman Cohen" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Stanley Norman Cohen</a> demonstrated that <a href="http://en.wikipedia.org/wiki/Restriction_enzyme" title="Restriction enzyme" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">restriction enzymes</a> could be used as "scissors" to cut <a href="http://en.wikipedia.org/wiki/DNA" title="DNA" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">DNA</a>fragments of interest from one source, to be ligated into a similarly cut <a href="http://en.wikipedia.org/wiki/Plasmid_vector" title="Plasmid vector" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">plasmid vector</a>.<sup id="cite_ref-6" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-6" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[6]</a></sup> While Cohen returned to the laboratory in academia, Swanson contacted Boyer to found the company.<sup id="cite_ref-Nature2003_01_23_4-1" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-Nature2003_01_23-4" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[4]</a></sup><sup id="cite_ref-7" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-7" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[7]</a></sup> Boyer worked with <a href="http://en.wikipedia.org/wiki/Arthur_Riggs(geneticist)" title="Arthur Riggs (geneticist)" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Arthur Riggs</a> and <a href="http://en.wikipedia.org/w/index.php?title=Keiichi_Itakura&action=edit&redlink=1" class="new" title="Keiichi Itakura (page does not exist)" style="text-decoration: none; color: rgb(165, 88, 88); background: none;">Keiichi Itakura</a> from the <a href="http://en.wikipedia.org/wiki/Beckman_Research_Institute" title="Beckman Research Institute" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Beckman Research Institute</a>, and the group became the first to successfully<a href="http://en.wikipedia.org/wiki/Gene_expression" title="Gene expression" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">express</a> a human <a href="http://en.wikipedia.org/wiki/Gene" title="Gene" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">gene</a> in <a href="http://en.wikipedia.org/wiki/Bacteria" title="Bacteria" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">bacteria</a> when they produced the <a href="http://en.wikipedia.org/wiki/Hormone" title="Hormone" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">hormone</a> <a href="http://en.wikipedia.org/wiki/Somatostatin" title="Somatostatin" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">somatostatin</a> in 1977.<sup id="cite_ref-8" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-8" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[8]</a></sup> <a href="http://en.wikipedia.org/wiki/David_Goeddel" title="David Goeddel" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">David Goeddel</a> and Dennis Kleid were then added to the group, and contributed to its success with synthetic human <a href="http://en.wikipedia.org/wiki/Insulin" title="Insulin" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">insulin</a> in 1978.</p><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);">The Swiss global health-care company <a href="http://en.wikipedia.org/wiki/Hoffmann-La_Roche" title="Hoffmann-La Roche" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">F. Hoffmann-La Roche AG</a> now completely owns Genentech after completing its purchase on March 26, 2009, for approximately $46.8 billion.<sup id="cite_ref-Morse_WSJ2006_9-0" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-Morse_WSJ2006-9" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[9]</a></sup><sup id="cite_ref-Staff_GEN2008_10-0" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-Staff_GEN2008-10" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[10]</a></sup></p><h2 style="font-weight: normal; margin: 1em 0px 0.25em; overflow: hidden; padding: 0px; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(170, 170, 170); font-family: 'Linux Libertine', Georgia, Times, serif; line-height: 1.3; background: none rgb(255, 255, 255);"><span class="mw-headline" id="Research">Research</span><span class="mw-editsection" style="-webkit-user-select: none; font-size: small; margin-left: 1em; vertical-align: baseline; line-height: 1em; display: inline-block; white-space: nowrap; unicode-bidi: -webkit-isolate; font-family: sans-serif;"><span class="mw-editsection-bracket" style="margin-right: 0px; color: rgb(85, 85, 85); margin-left: 0px;">[</span><a href="http://en.wikipedia.org/w/index.php?title=Genentech&action=edit&section=2" title="Edit section: Research" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">edit</a><span class="mw-editsection-bracket" style="margin-left: 0px; color: rgb(85, 85, 85); margin-right: 0px;">]</span></span></h2><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);">Genentech markets itself as a research-driven corporation that follows the science to make innovations. They employ more than 1,100 researchers, scientists and postdocs and cover a wide range of scientific activity—from molecular biology to protein chemistry to bioinformatics and physiology. Genentech scientists in these various areas of expertise currently focus their efforts on five disease categories: <a href="http://en.wikipedia.org/wiki/Oncology" title="Oncology" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Oncology</a>, <a href="http://en.wikipedia.org/wiki/Immunology" title="Immunology" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Immunology</a>, Tissue Growth and Repair, Neuroscience and Infectious Disease. Genentech's recent hiring and acquisitions indicate an intent to expand into <a href="http://en.wikipedia.org/wiki/Microbiology" title="Microbiology" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">microbiology</a> and <a href="http://en.wikipedia.org/wiki/Medical_Imaging" title="Medical Imaging" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">medical Imaging</a>.</p><h2 style="font-weight: normal; margin: 1em 0px 0.25em; overflow: hidden; padding: 0px; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(170, 170, 170); font-family: 'Linux Libertine', Georgia, Times, serif; line-height: 1.3; background: none rgb(255, 255, 255);"><span class="mw-headline" id="Facilities">Facilities</span><span class="mw-editsection" style="-webkit-user-select: none; font-size: small; margin-left: 1em; vertical-align: baseline; line-height: 1em; display: inline-block; white-space: nowrap; unicode-bidi: -webkit-isolate; font-family: sans-serif;"><span class="mw-editsection-bracket" style="margin-right: 0px; color: rgb(85, 85, 85); margin-left: 0px;">[</span><a href="http://en.wikipedia.org/w/index.php?title=Genentech&action=edit&section=3" title="Edit section: Facilities" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">edit</a><span class="mw-editsection-bracket" style="margin-left: 0px; color: rgb(85, 85, 85); margin-right: 0px;">]</span></span></h2><div class="thumb tright" style="clear: right; float: right; margin: 0.5em 0px 1.3em 1.4em; width: auto; color: rgb(37, 37, 37); font-size: 14px; line-height: 22.3999996185303px; background-color: rgb(255, 255, 255);"><div class="thumbinner" style="min-width: 100px; border: 1px solid rgb(204, 204, 204); padding: 3px; font-size: 13.1599998474121px; text-align: center; overflow: hidden; width: 222px; background-color: rgb(249, 249, 249);"><div class="thumbcaption" style="border: none; line-height: 1.4em; padding: 3px; font-size: 12.370400428772px; text-align: left;"><a href="http://en.wikipedia.org/wiki/File:Genentechheadquarters.jpg" class="internal" title="Enlarge" style="text-decoration: none; color: rgb(11, 0, 128); display: block; text-indent: 15px; white-space: nowrap; overflow: hidden; width: 15px; height: 11px; -webkit-user-select: none; background: linear-gradient(transparent, transparent), url(data:image/svg+xml,%3C%3Fxml%20version%3D%221.0%22%20encoding%3D%22UTF-8%22%20standalone%3D%22no%22%3F%3E%0A%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%2011%2015%22%20width%3D%2215%22%20height%3D%2211%22%3E%0A%20%20%20%20%3Cg%20id%3D%22magnify-clip%22%20fill%3D%22%23fff%22%20stroke%3D%22%23000%22%3E%0A%20%20%20%20%20%20%20%20%3Cpath%20id%3D%22bigbox%22%20d%3D%22M1.509%201.865h10.99v7.919h-10.99z%22%2F%3E%0A%20%20%20%20%20%20%20%20%3Cpath%20id%3D%22smallbox%22%20d%3D%22M-1.499%206.868h5.943v4.904h-5.943z%22%2F%3E%0A%20%20%20%20%3C%2Fg%3E%0A%3C%2Fsvg%3E%0A);">ilding 32, one of the Genentech headquarters' newer buildings</a></div></div></div><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);"><a href="http://en.wikipedia.org/wiki/File:Genentechheadquarters.jpg" class="internal" title="Enlarge" style="text-decoration: none; color: rgb(11, 0, 128); display: block; text-indent: 15px; white-space: nowrap; overflow: hidden; width: 15px; height: 11px; -webkit-user-select: none; background: linear-gradient(transparent, transparent), url(data:image/svg+xml,%3C%3Fxml%20version%3D%221.0%22%20encoding%3D%22UTF-8%22%20standalone%3D%22no%22%3F%3E%0A%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%2011%2015%22%20width%3D%2215%22%20height%3D%2211%22%3E%0A%20%20%20%20%3Cg%20id%3D%22magnify-clip%22%20fill%3D%22%23fff%22%20stroke%3D%22%23000%22%3E%0A%20%20%20%20%20%20%20%20%3Cpath%20id%3D%22bigbox%22%20d%3D%22M1.509%201.865h10.99v7.919h-10.99z%22%2F%3E%0A%20%20%20%20%20%20%20%20%3Cpath%20id%3D%22smallbox%22%20d%3D%22M-1.499%206.868h5.943v4.904h-5.943z%22%2F%3E%0A%20%20%20%20%3C%2Fg%3E%0A%3C%2Fsvg%3E%0A);">Genentech's corporate headquarters are in </a><a href="http://en.wikipedia.org/wiki/South_San_Francisco,California" title="South San Francisco, California" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">South San Francisco, California</a>, with additional manufacturing facilities in <a href="http://en.wikipedia.org/wiki/Vacaville,California" title="Vacaville, California" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Vacaville, California</a>, <a href="http://en.wikipedia.org/wiki/Oceanside,California" title="Oceanside, California" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Oceanside, California</a>, and <a href="http://en.wikipedia.org/wiki/Hillsboro,Oregon" title="Hillsboro, Oregon" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Hillsboro, Oregon</a>.</p><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);">In December 2006, Genentech sold its <a href="http://en.wikipedia.org/wiki/O_Porri%C3%B1o" title="O Porriño" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Porriño</a>, <a href="http://en.wikipedia.org/wiki/Spain" title="Spain" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Spain</a> facility to <a href="http://en.wikipedia.org/wiki/Lonza_Group" title="Lonza Group" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Lonza</a> and acquired an exclusive right to purchase Lonza's mammalian cell culture manufacturing facility under construction in <a href="http://en.wikipedia.org/wiki/Singapore" title="Singapore" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Singapore</a>. In June 2007, Genentech began the construction and development of an <i>E. coli</i> manufacturing facility, also in Singapore, for the worldwide production of <a href="http://en.wikipedia.org/wiki/Lucentis" title="Lucentis" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Lucentis</a> (<a href="http://en.wikipedia.org/wiki/Ranibizumab" title="Ranibizumab" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">ranibizumab</a> injection) bulk drug substance.</p><h2 style="font-weight: normal; margin: 1em 0px 0.25em; overflow: hidden; padding: 0px; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(170, 170, 170); font-family: 'Linux Libertine', Georgia, Times, serif; line-height: 1.3; background: none rgb(255, 255, 255);"><span class="mw-headline" id="Controversy">Controversy</span><span class="mw-editsection" style="-webkit-user-select: none; font-size: small; margin-left: 1em; vertical-align: baseline; line-height: 1em; display: inline-block; white-space: nowrap; unicode-bidi: -webkit-isolate; font-family: sans-serif;"><span class="mw-editsection-bracket" style="margin-right: 0px; color: rgb(85, 85, 85); margin-left: 0px;">[</span><a href="http://en.wikipedia.org/w/index.php?title=Genentech&action=edit&section=4" title="Edit section: Controversy" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">edit</a><span class="mw-editsection-bracket" style="margin-left: 0px; color: rgb(85, 85, 85); margin-right: 0px;">]</span></span></h2><h3 style="margin: 0.3em 0px 0px; overflow: hidden; padding-top: 0.5em; padding-bottom: 0px; border-bottom-style: none; line-height: 1.6; background: none rgb(255, 255, 255);"><span class="mw-headline" id="Disputes">Disputes</span><span class="mw-editsection" style="-webkit-user-select: none; font-size: small; font-weight: normal; margin-left: 1em; vertical-align: baseline; line-height: 1em; display: inline-block; white-space: nowrap; unicode-bidi: -webkit-isolate;"><span class="mw-editsection-bracket" style="margin-right: 0px; color: rgb(85, 85, 85); margin-left: 0px;">[</span><a href="http://en.wikipedia.org/w/index.php?title=Genentech&action=edit&section=5" title="Edit section: Disputes" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">edit</a><span class="mw-editsection-bracket" style="margin-left: 0px; color: rgb(85, 85, 85); margin-right: 0px;">]</span></span></h3><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);">In 2009, <i><a href="http://en.wikipedia.org/wiki/The_New_York_Times" title="The New York Times" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">The New York Times</a></i> reported that Genentech's talking points on <a href="http://en.wikipedia.org/wiki/Health_care_reform_in_the_United_States" title="Health care reform in the United States" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">health care reform</a> made it into the official statements of several Members of <a href="http://en.wikipedia.org/wiki/U.S.Congress" title="U.S. Congress" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Congress</a> during the health care debate.<sup id="cite_ref-11" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-11" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[11]</a></sup></p><p style="margin: 0.5em 0px; line-height: 22.3999996185303px; color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);">In 1999, Genentech agreed to pay the <a href="http://en.wikipedia.org/wiki/University_of_California,San_Francisco" title="University of California, San Francisco" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">University of California, San Francisco</a> $200 million to settle a nine-year-old patent dispute. In 1990, UCSF sued Genentech for $400 million in compensation for alleged theft of technology developed at the university and covered by a 1982 patent. Genentech claimed that they developed <a href="http://en.wikipedia.org/wiki/Protropin" title="Protropin" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Protropin</a>, a <a href="http://en.wikipedia.org/w/index.php?title=Growth_hormon&action=edit&redlink=1" class="new" title="Growth hormon (page does not exist)" style="text-decoration: none; color: rgb(165, 88, 88); background: none;">growth hormone</a>, independently of UCSF. A jury ruled that the university's patent was valid last July, but wasn't able to decide whether Protropin was based upon UCSF research or not. Protropin, a drug used to treat <a href="http://en.wikipedia.org/wiki/Dwarfism" title="Dwarfism" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">dwarfism</a>, was Genentech's first marketed drug and its $2 billion in sales has contributed greatly to its position as an industry leader. The settlement was to be divided as follows: $30 million to the <a href="http://en.wikipedia.org/wiki/University_of_California_finances" title="University of California finances" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">University of California General Fund</a>, $85 million to the three inventors and two collaborating scientists, $50 million towards a new teaching and research campus for UCSF, and $35 million to support university-wide research.<sup id="cite_ref-12" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-12" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[12]</a></sup></p><h2 style="font-weight: normal; margin: 1em 0px 0.25em; overflow: hidden; padding: 0px; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(170, 170, 170); font-family: 'Linux Libertine', Georgia, Times, serif; line-height: 1.3; background: none rgb(255, 255, 255);"><span class="mw-headline" id="Products_timeline">Products timeline</span><span class="mw-editsection" style="-webkit-user-select: none; font-size: small; margin-left: 1em; vertical-align: baseline; line-height: 1em; display: inline-block; white-space: nowrap; unicode-bidi: -webkit-isolate; font-family: sans-serif;"><span class="mw-editsection-bracket" style="margin-right: 0px; color: rgb(85, 85, 85); margin-left: 0px;">[</span><a href="http://en.wikipedia.org/w/index.php?title=Genentech&action=edit&section=6" title="Edit section: Products timeline" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">edit</a><span class="mw-editsection-bracket" style="margin-left: 0px; color: rgb(85, 85, 85); margin-right: 0px;">]</span></span></h2><ul style="line-height: 22.3999996185303px; margin: 0.3em 0px 0px 1.6em; padding: 0px; list-style-image: url(data:image/svg+xml,%3C%3Fxml%20version%3D%221.0%22%20encoding%3D%22UTF-8%22%3F%3E%0A%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20version%3D%221.1%22%20width%3D%225%22%20height%3D%2213%22%3E%0A%3Ccircle%20cx%3D%222.5%22%20cy%3D%229.5%22%20r%3D%222.5%22%20fill%3D%22%2300528c%22%2F%3E%0A%3C%2Fsvg%3E%0A); color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);"><li style="margin-bottom: 0.1em;">1982 - Synthetic "human" <a href="http://en.wikipedia.org/wiki/Insulin" title="Insulin" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">insulin</a> approved by the <a href="http://en.wikipedia.org/wiki/U.S.Food_and_Drug_Administration" title="U.S. Food and Drug Administration" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">U.S. Food and Drug Administration</a> (FDA), thanks largely to its partnership with insulin manufacturer <a href="http://en.wikipedia.org/wiki/Eli_Lilly_and_Company" title="Eli Lilly and Company" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Eli Lilly and Company</a>, who shepherded the product through the FDA approval process. The product (<a href="http://en.wikipedia.org/wiki/Humulin" title="Humulin" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Humulin</a>) was licensed to and manufactured by Lilly, and was the first-ever approved genetically engineered human therapeutic.</li><li style="margin-bottom: 0.1em;">1985 - <a href="http://en.wikipedia.org/wiki/Protropin" title="Protropin" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Protropin</a> (somatrem) - Supplementary <a href="http://en.wikipedia.org/wiki/Growth_hormone" title="Growth hormone" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">growth hormone</a> for children with <a href="http://en.wikipedia.org/wiki/Growth_hormone_deficiency" title="Growth hormone deficiency" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">growth hormone deficiency</a> (ceased manufacturing 2004).</li><li style="margin-bottom: 0.1em;">1987 - <a href="http://en.wikipedia.org/wiki/Activase" title="Activase" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Activase</a> (alteplase) - A recombinant <a href="http://en.wikipedia.org/wiki/Tissue_plasminogen_activator" title="Tissue plasminogen activator" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">tissue plasminogen activator</a> (tPa) used to dissolve blood clots in patients with acute <a href="http://en.wikipedia.org/wiki/Myocardial_infarction" title="Myocardial infarction" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">myocardial infarction</a>. Also used to treat non-hemorrhagic stroke.</li><li style="margin-bottom: 0.1em;">1990 - <a href="http://en.wikipedia.org/wiki/Actimmune" title="Actimmune" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Actimmune</a> (<a href="http://en.wikipedia.org/wiki/Interferon" title="Interferon" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">interferon gamma 1b</a>) - Treatment of <a href="http://en.wikipedia.org/wiki/Chronic_granulomatous_disease" title="Chronic granulomatous disease" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">chronic granulomatous disease</a> (licensed to <a href="http://en.wikipedia.org/w/index.php?title=Intermune&action=edit&redlink=1" class="new" title="Intermune (page does not exist)" style="text-decoration: none; color: rgb(165, 88, 88); background: none;">Intermune</a>).</li><li style="margin-bottom: 0.1em;">1993 - <a href="http://en.wikipedia.org/wiki/Nutropin" title="Nutropin" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Nutropin</a> (recombinant somatropin) - <a href="http://en.wikipedia.org/wiki/Growth_hormone" title="Growth hormone" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Growth hormone</a> for children and adults for treatment before <a href="http://en.wikipedia.org/wiki/Kidney_transplant" title="Kidney transplant" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">kidney transplant</a> due to chronic renal insufficiency.</li><li style="margin-bottom: 0.1em;">1993 - <a href="http://en.wikipedia.org/wiki/Pulmozyme" title="Pulmozyme" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Pulmozyme</a> (dornase alfa) - Inhalation treatment for children and young adults with <a href="http://en.wikipedia.org/wiki/Cystic_fibrosis" title="Cystic fibrosis" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">cystic fibrosis</a> - recombinant <a href="http://en.wikipedia.org/wiki/DNAse" title="DNAse" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">DNAse</a>.</li><li style="margin-bottom: 0.1em;">1997 - <a href="http://en.wikipedia.org/wiki/Rituximab" title="Rituximab" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Rituxan</a> (rituximab) - Treatment for specific kinds of <a href="http://en.wikipedia.org/wiki/Non-Hodgkins_lymphomas" title="Non-Hodgkins lymphomas" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">non-Hodgkins lymphomas</a>. In 2006, also approved for rheumatoid arthritis.</li><li style="margin-bottom: 0.1em;">1998 - <a href="http://en.wikipedia.org/wiki/Trastuzumab" title="Trastuzumab" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Herceptin</a> (trastuzumab) - Treatment for <a href="http://en.wikipedia.org/wiki/Metastatic_breast_cancer" title="Metastatic breast cancer" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">metastatic breast cancer</a> patients with tumors that overexpress the <a href="http://en.wikipedia.org/wiki/HER2" title="HER2" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">HER2</a> gene. Recently approved for adjuvant therapy for breast cancer. FDA also recently approved Trastuzumab for metastatic gastric cancer with HER2 receptor site positive.</li><li style="margin-bottom: 0.1em;">2000 - <a href="http://en.wikipedia.org/wiki/TNKase" title="TNKase" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">TNKase</a> (tenecteplase) - "<a href="http://en.wikipedia.org/wiki/Thrombolysis" title="Thrombolysis" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Clot-busting</a>" drug to treat acute <a href="http://en.wikipedia.org/wiki/Myocardial_infarction" title="Myocardial infarction" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">myocardial infarction</a>.</li><li style="margin-bottom: 0.1em;">2003 - <a href="http://en.wikipedia.org/wiki/Omalizumab" title="Omalizumab" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Xolair</a> (omalizumab) - Subcutaneous injection for moderate to severe persistent <a href="http://en.wikipedia.org/wiki/Asthma" title="Asthma" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">asthma</a>.</li><li style="margin-bottom: 0.1em;">2003 - <a href="http://en.wikipedia.org/wiki/Efalizumab" title="Efalizumab" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Raptiva</a> (efalizumab) - Antibody designed to block the activation and reactivation of <a href="http://en.wikipedia.org/wiki/T_cell" title="T cell" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">T cells</a> that lead to the development of <a href="http://en.wikipedia.org/wiki/Psoriasis" title="Psoriasis" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">psoriasis</a>. Developed in partnership with <a rel="nofollow" class="external text" href="http://www.xoma.com/" style="text-decoration: none; color: rgb(102, 51, 102); padding-right: 13px; background: linear-gradient(transparent, transparent) 100% 50% no-repeat, url(data:image/svg+xml,%3C%3Fxml%20version%3D%221.0%22%20encoding%3D%22UTF-8%22%3F%3E%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20width%3D%2210%22%20height%3D%2210%22%3E%3Cg%20transform%3D%22translate%28-826.429%20-698.791%29%22%3E%3Crect%20width%3D%225.982%22%20height%3D%225.982%22%20x%3D%22826.929%22%20y%3D%22702.309%22%20fill%3D%22%23fff%22%20stroke%3D%22%2306c%22%2F%3E%3Cg%3E%3Cpath%20d%3D%22M831.194%20698.791h5.234v5.391l-1.571%201.545-1.31-1.31-2.725%202.725-2.689-2.689%202.808-2.808-1.311-1.311z%22%20fill%3D%22%2306f%22%2F%3E%3Cpath%20d%3D%22M835.424%20699.795l.022%204.885-1.817-1.817-2.881%202.881-1.228-1.228%202.881-2.881-1.851-1.851z%22%20fill%3D%22%23fff%22%2F%3E%3C%2Fg%3E%3C%2Fg%3E%3C%2Fsvg%3E) 100% 50%;">XOMA</a>. In 2009, voluntary U.S. market withdrawal after reports of <a href="http://en.wikipedia.org/wiki/Progressive_multifocal_leukoencephalopathy" title="Progressive multifocal leukoencephalopathy" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">progressive multifocal leukoencephalopathy</a>.</li><li style="margin-bottom: 0.1em;">2004 - <a href="http://en.wikipedia.org/wiki/Bevacizumab" title="Bevacizumab" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Avastin</a> (bevacizumab) - Anti-VEGF <a href="http://en.wikipedia.org/wiki/Monoclonal_antibody" title="Monoclonal antibody" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">monoclonal antibody</a> for the treatment of metastatic cancer of the <a href="http://en.wikipedia.org/wiki/Colon(anatomy)" title="Colon (anatomy)" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">colon</a> or <a href="http://en.wikipedia.org/wiki/Rectum" title="Rectum" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">rectum</a>. In 2006, also approved for locally advanced, recurrent or metastatic <a href="http://en.wikipedia.org/wiki/Non-small_cell_lung_cancer" title="Non-small cell lung cancer" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">non-small cell lung cancer</a>. In 2008, accelerated approval was granted for Avastin in combination with chemotherapy for previously untreated advanced HER2-negative breast cancer. In 2009, Avastin gained its fifth approval for treatment of <a href="http://en.wikipedia.org/wiki/Glioblastoma_multiforme" title="Glioblastoma multiforme" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">glioblastoma multiforme</a>, and sixth approval for the treatment of metastatic <a href="http://en.wikipedia.org/wiki/Renal_cell_carcinoma" title="Renal cell carcinoma" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">renal cell carcinoma</a>. It was most publicized for its approval in advanced breast cancer treatment, but the FDA approval for breast cancer treatment was subsequently revoked in November, 2011.</li><li style="margin-bottom: 0.1em;">2004 - <a href="http://en.wikipedia.org/wiki/Erlotinib" title="Erlotinib" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Tarceva</a> (erlotinib) - Treatment for patients with locally advanced or metastatic non-small cell lung cancer, and pancreatic cancer.</li><li style="margin-bottom: 0.1em;">2006 - <a href="http://en.wikipedia.org/wiki/Ranibizumab" title="Ranibizumab" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Lucentis</a> (ranibizumab injection) - Treatment of neovascular (wet) age-related macular degeneration (AMD). The FDA approved LUCENTIS after a Priority Review (six-month). Genentech started shipping product on June 30, 2006, the day the product was approved.</li><li style="margin-bottom: 0.1em;">2010 - <a href="http://en.wikipedia.org/wiki/Actemra" title="Actemra" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Actemra</a> (tocilizumab) - The first interleukin-6 (IL-6) receptor-inhibiting monoclonal antibody approved to treat rheumatoid arthritis (RA).</li><li style="margin-bottom: 0.1em;">2012 - <a href="http://en.wikipedia.org/wiki/Erivedge" title="Erivedge" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Erivedge</a> (vismodegib) - Treatment for advanced <a href="http://en.wikipedia.org/wiki/Basal-cell_carcinoma" title="Basal-cell carcinoma" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">basal-cell carcinoma</a> (BCC). A small molecule inhibitor that targets a key protein in the <a href="http://en.wikipedia.org/wiki/Hedgehog_signaling_pathway" title="Hedgehog signaling pathway" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Hedgehog signaling pathway</a>. This is the first approved therapy for advanced BCC.</li><li style="margin-bottom: 0.1em;">2012 - <a href="http://en.wikipedia.org/wiki/Pertuzumab" title="Pertuzumab" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">PERJETA</a> (pertuzumab) - For use in combination with Herceptin (trastuzumab) and <a href="http://en.wikipedia.org/wiki/Docetaxel" title="Docetaxel" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">docetaxel</a> chemotherapy for the treatment of patients with previously untreated HER2-positive metastatic breast cancer.</li><li style="margin-bottom: 0.1em;">2013 - <a href="http://en.wikipedia.org/wiki/Trastuzumab_emtansine" title="Trastuzumab emtansine" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Kadcyla</a> (ado-trastuzumab emtansine) - The first Genentech antibody-drug conjugate (ADC) to receive FDA approval. It consists of trastuzumab (Herceptin) linked to a cytotoxic agent mertansine (DM1), used in the treatment of HER2-positive metastatic breast cancer.</li><li style="margin-bottom: 0.1em;">2013 - <a href="http://en.wikipedia.org/wiki/Obinutuzumab" title="Obinutuzumab" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Gazyva</a> (obinutuzumab) - For use in combination with chlorambucil to treat patients with previously untreated <a href="http://en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia" title="Chronic lymphocytic leukemia" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">chronic lymphocytic leukemia</a> (CLL). Gazyva is the first drug with breakthrough therapy designation to receive FDA approval.</li><li style="margin-bottom: 0.1em;">Ongoing Work - Genentech is working on <a href="http://en.wikipedia.org/wiki/DR6" title="DR6" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">DR6</a> blocking and anti-N-<a href="http://en.wikipedia.org/wiki/Amyloid_precursor_protein" title="Amyloid precursor protein" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">APP</a> monoclonal antibodies as a potential treatment to delay progression of neuronal destruction in early <a href="http://en.wikipedia.org/wiki/Alzheimer%27s_disease" title="Alzheimer's disease" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Alzheimer's disease</a>. To the extent that prevention of neuronal destruction via DR-6 and N-APP would require ongoing intervention, the effective half-life of any monoclonal antibody treatment would have to be substantial. An siRNA approach against DR-6, or vaccine against N-APP may circumvent these limitations.</li></ul><h2 style="font-weight: normal; margin: 1em 0px 0.25em; overflow: hidden; padding: 0px; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(170, 170, 170); font-family: 'Linux Libertine', Georgia, Times, serif; line-height: 1.3; background: none rgb(255, 255, 255);"><span class="mw-headline" id="Awards_and_recognitions">Awards and recognitions</span><span class="mw-editsection" style="-webkit-user-select: none; font-size: small; margin-left: 1em; vertical-align: baseline; line-height: 1em; display: inline-block; white-space: nowrap; unicode-bidi: -webkit-isolate; font-family: sans-serif;"><span class="mw-editsection-bracket" style="margin-right: 0px; color: rgb(85, 85, 85); margin-left: 0px;">[</span><a href="http://en.wikipedia.org/w/index.php?title=Genentech&action=edit&section=7" title="Edit section: Awards and recognitions" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">edit</a><span class="mw-editsection-bracket" style="margin-left: 0px; color: rgb(85, 85, 85); margin-right: 0px;">]</span></span></h2><ul style="line-height: 22.3999996185303px; margin: 0.3em 0px 0px 1.6em; padding: 0px; list-style-image: url(data:image/svg+xml,%3C%3Fxml%20version%3D%221.0%22%20encoding%3D%22UTF-8%22%3F%3E%0A%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20version%3D%221.1%22%20width%3D%225%22%20height%3D%2213%22%3E%0A%3Ccircle%20cx%3D%222.5%22%20cy%3D%229.5%22%20r%3D%222.5%22%20fill%3D%22%2300528c%22%2F%3E%0A%3C%2Fsvg%3E%0A); color: rgb(37, 37, 37); font-size: 14px; background-color: rgb(255, 255, 255);"><li style="margin-bottom: 0.1em;"><i><a href="http://en.wikipedia.org/wiki/Fortune_Magazine" title="Fortune Magazine" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Fortune Magazine</a></i> named Genentech number one on its 2006 list of the "100 Best Companies To Work For." This was the first number one ranking for the company, which has now been on the list for 17 consecutive years. In 2007, it dropped to second place, behind Google. The company ranked 5th in 2008, 7th in 2009, 19th in 2010, 35th in 2011, 68th in 2012, 36th in 2013, 6th in 2014, and 9th in 2015. The ranking is based on anonymous employee responses to a survey as well as an evaluation of the company's policies and culture.</li><li style="margin-bottom: 0.1em;">Genentech was named one of the 100 Best Companies for Working Mothers in 2004, 2006-8 and 2010-11 by <i>Working Mother Magazine</i>.<sup id="cite_ref-13" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-13" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[13]</a></sup></li><li style="margin-bottom: 0.1em;">It was named as one of the 100 best corporate citizens 2006 by the <i><a href="http://en.wikipedia.org/w/index.php?title=Business_Ethics_Magazine&action=edit&redlink=1" class="new" title="Business Ethics Magazine (page does not exist)" style="text-decoration: none; color: rgb(165, 88, 88); background: none;">Business Ethics Magazine</a></i>. The company participates in various policy and civic leadership groups, such as TechNet,<sup id="cite_ref-14" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-14" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[14]</a></sup> and sponsors independent third-party research and publications, such as the journal <i><a href="http://en.wikipedia.org/wiki/Nature(journal)" title="Nature (journal)" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Nature</a></i>.<sup id="cite_ref-15" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-15" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[15]</a></sup></li><li style="margin-bottom: 0.1em;">Genentech was named Top Employer by <i>Science Magazine</i> on October 7, 2010, where it has been recognized for nine consecutive years.<sup id="cite_ref-16" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-16" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[16]</a></sup></li><li style="margin-bottom: 0.1em;">In March 2008, Genentech was named Most Admired Pharmaceutical Company by Fortune for the second consecutive year.</li><li style="margin-bottom: 0.1em;">In July 2010, Genentech was named on the "Top 100 Best Places to Work in IT" list by <i>ComputerWorld</i> magazine.<sup id="cite_ref-17" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-17" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[17]</a></sup></li><li style="margin-bottom: 0.1em;">In December 2008, <a href="http://en.wikipedia.org/wiki/Glassdoor.com" title="Glassdoor.com" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Glassdoor.com</a> rated the Genentech CEO <a href="http://en.wikipedia.org/wiki/Arthur_D.Levinson" title="Arthur D. Levinson" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Arthur D. Levinson</a> as the "nicest" CEO of 2008 with a 93% approval rating.<sup id="cite_ref-18" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-18" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[18]</a></sup></li><li style="margin-bottom: 0.1em;">Genentech was featured in the documentary film <a href="http://en.wikipedia.org/wiki/Something_Ventured_(film)" title="Something Ventured (film)" class="mw-redirect" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">Something Ventured</a> which premiered in 2011.</li><li style="margin-bottom: 0.1em;"><i><a href="http://en.wikipedia.org/wiki/The_Economist" title="The Economist" style="text-decoration: none; color: rgb(11, 0, 128); background: none;">The Economist</a></i> rated Genentech as the Most Innovative Corporation of 2013.<sup id="cite_ref-19" class="reference" style="line-height: 1; unicode-bidi: -webkit-isolate; font-size: 11.1999998092651px;"><a href="http://en.wikipedia.org/wiki/Genentech#cite_note-19" style="text-decoration: none; color: rgb(11, 0, 128); white-space: nowrap; background: none;">[19]</a></sup></li></ul><h2 style="font-weight: normal; margin: 1em 0px 0.25em; overflow: hidden; padding: 0px; border-bottom-width: 1px; border-bottom-style: solid; border-bottom-color: rgb(170, 170, 170); font-family: 'Linux Libertine', Georgia, Times, serif; line-height: 1.3; background: none rgb(255, 255, 255);">
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