Main Overview
Hormones (detailed)
Types of Hormones
ACTH
2 Circulatory System, Blood Pressure, Blood Volume and Blood Pressure Signaling Effects
1 Circulatory Impairment, Disease and Irregularities
+4 White Blood Cells/Leukocytes/Mast Cells/Immune Cells
Dysregulation of the Interferon Pathway
Antiviral Pathway Deregulation of Chronic Fatigue Syndrome Induces Nitric Oxide Production in Immune Cells That Precludes a Resolution of the Inflammatory Response

+1a Inflamation

Parents

1a) Stress Response System
8 Chronic Immune Activation
Antiviral Pathway Deregulation of Chronic Fatigue Syndrome Induces Nitric Oxide Production in Immune Cells That Precludes a Resolution of the Inflammatory Response
Continued Stress
Initiation of Inflammation after TBI

+1 Neuroinflammation
1a Decreases in Sphingolipid, glycosphingolipid, phospholipid, purine, microbiome aromatic amino acid and branch chain amino acid metabolites, as well as in flavine adenine nucleotide (FAD) and lathosterol
Activated Immune-Inflammatory and Oxidative and Nitrosative Pathways
Antiviral Pathway Deregulation of Chronic Fatigue Syndrome Induces Nitric Oxide Production in Immune Cells That Precludes a Resolution of the Inflammatory Response
Autoimmune and Metabolic Pathway Abnormalities
Cytokine Inflamation
Endothelial Dysfunction
extracellular secretion of mitochondrial DNA
Leaky gut (intestinal permeability)
Low Level Inflamation (on-going state of low level over-activity)
polymorphonuclear neutrophils (PMNs) at the site of inflammation causes endothelial dysfunction and tissue injury
ROS (and Ros mediated damage)
Stimulation of Hypothalamic Mast Cells by Environmental Neuroimmune Pathogenic And stress triggers activates microglia leading to focal inflammation in the brain
z Inflamation