Fred's Protocol
<p>From user Jay on: 'My Protocol to Cure Chronic Fatigue and Fatigue After Meals' <a href="https://selfhacked.com/blog/my-cutting-edge-protocol-to-cure-fatigue/">https://selfhacked.com/blog/my-cutting-edge-protocol-to-cure-fatigue/</a></p>
<p>
He proposes that some people with severe CFS-like symptoms likely have troubles in their body with conversions to the active B12s (methylcobalamin & adenosylcobalamin) and active folate (“methylfolate”). He further suggests that some may have issues with even folinic acid or any non-animal dietary folates, and that these may block the activity of active folate. Lack of folate can further compound B12 deficiencies, and it becomes a vicious cycle. For people with these problems, consuming lots of folic acid (which is hard to avoid in modern food) as a child and growing up can wreak havoc, especially when coupled with other stressors. He suggests a protocol of what he calls the deadlock quartet (methylB12, adenosylB12, methylFolate, l-carnitine fumarate), ample potassium and other cofactors (vitamins, minerals, omega3s, ala, sam-e, etc.), and he further recommends restricting non-animal dietary folates.</p>
<p>
I’ve grown partial to his views given my own experiences having long-term issues with IBS, histamine, fatigue, brain fog, weakness, being underweight, poor appetite, etc. Low-lectin diets, elemental diet, leaky gut protocols, candida protocols all provided minimal relief. I don’t follow his protocol exactly, because the rapid healing symptoms can be uncomfortable and balancing of cofactors and avoiding potassium deficiency can be complicated. I’ve been eating chicken liver (for active B12s & folate, and less copper than beef), chicken breast, safflower oil, macadamia nuts, rice milk(not fortified) and corn cereal(not fortified), and supplementing Vitamin D, fish oil, calcium and zinc (thinking of adding molybdenum and Vitamin K). This provides a balanced diet with minimal non-animal folate, while still avoiding the more inflammatory foods. So far, the results have been quite significant in terms of energy and clarity, and a little less so with the digestive issues, but still quite improved. Many claim dramatic results, and Freddd himself claims to have pretty much cured himself of severe CFS.</p>
<p>
Trying out Freddd’s ideas, whether through supplements or diet, is relatively cheap compared to other CFS protocols, and, as I said, results can be dramatic. His ideas are quite popular on CFS and MTHFR forums, but I haven’t seen anything related on your blog. I thought I’d bring it up as something to possibly experiment with yourself or recommend to certain clients.
</p>