Trichopoulos, D

<ul style="font-size: 13px; line-height: 19.200000762939453px; list-style-type: square; margin: 0.3em 0px 0px 1.6em; padding: 0px; list-style-image: url(data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAUAAAANCAMAAABW4lS6AAAAGXRFWHRTb2Z0d2FyZQBBZG9iZSBJbWFnZVJlYWR5ccllPAAAAAZQTFRFAFKM////QIUK9QAAAAJ0Uk5T/wDltzBKAAAAGklEQVR42mJgBAEGokgGBjBGBxBxsBqAAAMACHwALd5r8ygAAAAASUVORK5CYII=); background-color: rgb(255, 255, 255);"><li style="margin-bottom: 0.1em;"><b><a href="http://www.powerbase.info/index.php?title=Dimitrios_Trichopoulos&action=edit&redlink=1" class="new" title="Dimitrios Trichopoulos (page does not exist)" style="text-decoration: none; color: rgb(165, 88, 88); outline: none; background: none;">Dimitrios Trichopoulos</a>, M.D., Harvard School of Public Health</b></li></ul><div><span style="font-size: 12.800000190734863px; line-height: 19.200000762939453px;"><b>=</b></span></div><div><span style="font-size: 12.800000190734863px; line-height: 19.200000762939453px;"><b>
</b></span></div><div><p style="margin: 1em 0px; padding: 0px; border: 0px; vertical-align: baseline; font-size: 13px; color: rgb(34, 34, 34); font-family: Arial, Helvetica, sans-serif; background-color: rgb(255, 255, 255);">Dimitrios Trichopoulos and Philip Cole both participated in the
dioxin detoxification campaign orchestrated by Exponent.</p><p style="margin: 1em 0px; padding: 0px; border: 0px; vertical-align: baseline; font-size: 13px; color: rgb(34, 34, 34); font-family: Arial, Helvetica, sans-serif; background-color: rgb(255, 255, 255);">Atrazine</p><p style="margin: 1em 0px; padding: 0px; border: 0px; vertical-align: baseline; font-size: 13px; color: rgb(34, 34, 34); font-family: Arial, Helvetica, sans-serif; background-color: rgb(255, 255, 255);">Trichopoulos also participates in the work on atrazine, as well as
Jack Mandel. It's noteworthy, that Mandel is presented as an academic
with "direct ties" to Exponent, as if he is a professor taking
commissions for that firm. Actually Jack Mandel is Group Vice
President and a senior consultant at Exponent. The third named
participant on the atrazine issue is Harris Pastides. He also
participated in the dioxin detoxification campaign, beeing co-author
of both reviews from Exponent.</p><p style="margin: 1em 0px; padding: 0px; border: 0px; vertical-align: baseline; font-size: 13px; color: rgb(34, 34, 34); font-family: Arial, Helvetica, sans-serif; background-color: rgb(255, 255, 255);">Adami gives the following additional comments on the atrazine project
in the second response to Wigzell (my translation):</p><p style="margin: 1em 0px; padding: 0px; border: 0px; vertical-align: baseline; font-size: 13px; color: rgb(34, 34, 34); font-family: Arial, Helvetica, sans-serif; background-color: rgb(255, 255, 255);">"The review of atrazine is interesting both by being representative
for the kind of consultancies I have accepted and because it offers
an interesting challenge which with good reason can be said to
demand an epidemiological competence which rarely is found within
the industry itself. Shortly, the background was that newly discovered
prostate cancer was found in excess to what was expected at the
plant in question producing atrazine. The basic question was therefore
if this was best explained by a carcinogenic effect on the prostate
from atrazine or by the fact that all employees were offered free
health controls with PSA testing. In a first document these two
alternative explanations were penetrated. In the second phase the
aim is to go one step further by performing a formal epidemiological
study aiming at quantification the effect of atrazine and PSA testing
respectively on the incidence of prostate cancer. This is proving
to be a delicate methodological issue, and my latest "review" on
the subject is about these aspects. I attach it as requested from
Bo Walhjalt." [11]</p><p style="margin: 1em 0px; padding: 0px; border: 0px; vertical-align: baseline; font-size: 13px; color: rgb(34, 34, 34); font-family: Arial, Helvetica, sans-serif; background-color: rgb(255, 255, 255);">The trickiness of the suggested case-control study is in part due
to the small number of cases, 17. In the Exponent review Dioxin and
Cancer Adami et al. discusses case-control studies showing increased
risk for cancer from exposure to dioxins. In a response to Dagens
Forskning Adami refers to this review because he is co-author of
one of these studies. He writes:</p><p style="margin: 1em 0px; padding: 0px; border: 0px; vertical-align: baseline; font-size: 13px; color: rgb(34, 34, 34); font-family: Arial, Helvetica, sans-serif; background-color: rgb(255, 255, 255);">"The uncertainty about dioxin arises from the indisputable cancerogenic
effect in animal trials, while the epidemiological support for a
similar effect in humans has been classified as "limited" by the
IARC. Also it has been remarkably hard to confirm among other things
the positive findings of Swedish researchers in international
epidemiological studies. Therefore I have accepted a commission to
review the methodology of the Swedish studies - a commission with
elements of self criticism since I'm co-author of an early study
limited to soft tissue sarcomas. My conclusion is that these studies
because of methodological shortcomings do not allow conclusions
about a causal relationship between dioxin and cancer." [12]</p><p style="margin: 1em 0px; padding: 0px; border: 0px; vertical-align: baseline; font-size: 13px; color: rgb(34, 34, 34); font-family: Arial, Helvetica, sans-serif; background-color: rgb(255, 255, 255);">In Dioxin and Cancer there is only a short dismissal of the positive
Swedish studies. It reads:....</p><p style="margin: 1em 0px; padding: 0px; border: 0px; vertical-align: baseline; background-color: rgb(255, 255, 255);"><font color="#222222" face="Arial, Helvetica, sans-serif"><span style="font-size: 12.800000190734863px;">https://groups.google.com/forum/#!topic/misc.activism.progressive/9r4vKdiBYCg</span></font></p></div><div><span style="font-size: 12.800000190734863px; line-height: 19.200000762939453px;"><b>=</b></span></div><div><header style="margin: 0px; padding: 0px; border: 0px; font-family: 'palatino linotype', palatino, serif; font-size: 15px; line-height: 22.5px; vertical-align: baseline; color: rgb(31, 30, 31); background-color: rgb(238, 221, 170);"><h1 class="entry-title" itemprop="headline" style="margin: 0px 0px 5px; padding: 5px 0px 1px; border-width: 4px 0px 0px; border-style: double; border-color: rgb(0, 85, 68); font-size: 28px; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: 33.599998474121094px; vertical-align: baseline; color: rgb(136, 0, 34); max-width: 100%; word-wrap: break-word; text-shadow: rgb(150, 149, 148) 2px 2px 4px;">iPRI Statement</h1><div class="entry-meta entry-meta-above" style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: 12px; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: inherit; vertical-align: baseline; color: rgb(110, 109, 109);">Posted on&nbsp;<time class="entry-date published updated" itemprop="datePublished" datetime="2014-04-01T18:49:16+00:00" style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: inherit; vertical-align: baseline;">April 1, 2014</time>&nbsp;by&nbsp;<span class="entry-author vcard" itemprop="author" itemscope="" itemptype="http://schema.org/Person" style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: inherit; vertical-align: baseline;"><a class="author-link fn nickname url" href="http://www.i-pri.org/author/editor/" title="View all posts by Editor" itemprop="url" style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-variant: inherit; line-height: inherit; vertical-align: baseline; outline: none; z-index: 2; text-decoration: none;">Editor</a></span>&nbsp;•&nbsp;<a href="http://www.i-pri.org/ipri-statement/#comments" title="iPRI Statement – Comments" class="entry-comments" style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-variant: inherit; line-height: inherit; vertical-align: baseline; outline: none; z-index: 2; text-decoration: none;">0 Comments</a></div></header><div class="entry-content" itemprop="text" style="margin: 20px 0px; padding: 0px; border: 0px; font-family: 'palatino linotype', palatino, serif; font-size: 15px; line-height: 22.5px; vertical-align: baseline; width: 840px; box-sizing: border-box; left: 0px; top: 0px; position: relative; z-index: 1; text-align: justify; background-color: rgb(238, 221, 170);"><p style="margin: 0px 0px 15px; padding: 0px; border: 0px; font-family: inherit; font-size: 15px; font-style: inherit; font-variant: inherit; font-weight: inherit; vertical-align: baseline; left: 0px; top: 0px; position: relative; z-index: 1;">In the interest of transparency, iPRI wishes it to be made known that the publications below which cite ‘an unrestricted research grant’ were neither iPRI approved studies nor was iPRI in anyway associated with the research grant.</p><p align="center" style="margin: 0px 0px 15px; padding: 0px; border: 0px; font-family: inherit; font-size: 15px; font-style: inherit; font-variant: inherit; font-weight: inherit; vertical-align: baseline; left: 0px; top: 0px; position: relative; z-index: 1;"><strong style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; vertical-align: baseline;">Articles in Question</strong></p><p style="margin: 0px 0px 15px; padding: 0px; border: 0px; font-family: inherit; font-size: 15px; font-style: inherit; font-variant: inherit; vertical-align: baseline; left: 0px; top: 0px; position: relative; z-index: 1;"><span style="font-weight: inherit;">Boffetta P, Adami HO, Cole P, </span><b><font color="#ff0000">Trichopoulos D</font></b><span style="font-weight: inherit;">, Mandel JS. Epidemiologic studies of styrene and cancer: a review of the literature. J Occup Environ Med. 2009 Nov;51(11):1275-87. [</span><a href="http://www.ncbi.nlm.nih.gov/pubmed/19858749" target="self" style="font-weight: inherit; margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-variant: inherit; line-height: inherit; vertical-align: baseline; outline: none; color: rgb(69, 0, 20); z-index: 2; text-decoration: none;">PMID: 19858749</a><span style="font-weight: inherit;">]</span></p><p style="margin: 0px 0px 15px; padding: 0px; border: 0px; font-family: inherit; font-size: 15px; font-style: inherit; font-variant: inherit; font-weight: inherit; vertical-align: baseline; left: 0px; top: 0px; position: relative; z-index: 1;"><strong style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; vertical-align: baseline;" />Boffetta P, Mundt KA, Adami HO, Cole P, Mandel JS. TCDD and cancer: A critical review of epidemiologic studies. Crit Rev Toxicol. 2011 Aug;41(7):622-36. [<a href="http://www.ncbi.nlm.nih.gov/pubmed/21718216" target="self" style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-variant: inherit; line-height: inherit; vertical-align: baseline; outline: none; color: rgb(69, 0, 20); z-index: 2; text-decoration: none;">PMID:21718216</a>]</p><p style="margin: 0px 0px 15px; padding: 0px; border: 0px; font-family: inherit; font-size: 15px; font-style: inherit; font-variant: inherit; font-weight: inherit; vertical-align: baseline; left: 0px; top: 0px; position: relative; z-index: 1;"><span style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; vertical-align: baseline;">Boffetta P, Fryzek JP, Mandel JS. Occupational exposure to beryllium and cancer risk: A review of the epidemiologic evidence. Crit Rev Toxicol. 2012 Feb;42(2):107-18. [</span><a href="http://www.ncbi.nlm.nih.gov/pubmed/22276590" target="_self" style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-variant: inherit; vertical-align: baseline; outline: none; color: rgb(69, 0, 20); z-index: 2; text-decoration: none;">PMID:22276590</a><span style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; vertical-align: baseline;">]</span></p><p style="margin: 0px 0px 15px; padding: 0px; border: 0px; font-family: inherit; font-size: 15px; font-style: inherit; font-variant: inherit; vertical-align: baseline; left: 0px; top: 0px; position: relative; z-index: 1;"><span style="font-weight: inherit;">Boffetta P, </span><b>Adami HO</b><span style="font-weight: inherit;">, Berry SC, Mandel JS. Atrazine and cancer: a review of the epidemiologic evidence. Eur J Cancer Prev. 2013 Mar;22(2):169-80. [</span><a title="Pubmed abstract" href="http://www.ncbi.nlm.nih.gov/pubmed/22914097" style="font-weight: inherit; margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-variant: inherit; line-height: inherit; vertical-align: baseline; outline: none; color: rgb(69, 0, 20); z-index: 2; text-decoration: none;">PMID:22914097</a><span style="font-weight: inherit;">]</span></p><p style="margin: 0px 0px 15px; padding: 0px; border: 0px; font-family: inherit; font-size: 15px; font-style: inherit; font-variant: inherit; font-weight: inherit; vertical-align: baseline; left: 0px; top: 0px; position: relative; z-index: 1;">Boffetta P. Lack of association between occupational exposure to diesel exhaust and risk of pancreatic cancer: a systematic evaluation of available data. Int Arch Occup Environ Health. 2013 Jul 13. [Epub ahead of print] [<a title="Pubmed abstract" href="http://www.ncbi.nlm.nih.gov/pubmed/23851578" style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-variant: inherit; line-height: inherit; vertical-align: baseline; outline: none; color: rgb(69, 0, 20); z-index: 2; text-decoration: none;">PMID:23851578</a>]</p><p style="margin: 0px 0px 15px; padding: 0px; border: 0px; font-family: inherit; font-size: 15px; font-style: inherit; font-variant: inherit; font-weight: inherit; vertical-align: baseline; left: 0px; top: 0px; position: relative; z-index: 1;">La Vecchia C and Boffetta P. Role of stopping exposure and recent exposure to asbestos in the risk of mesothelioma. Eur J Cancer Prev. 2012 May;21(3):227-30. doi: 10.1097/CEJ.0b013e32834dbc56.</p></div></div><div><span style="font-size: 12.800000190734863px; line-height: 19.200000762939453px;"><b>===</b></span></div>