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Subjective Cognitive Impairment

Individuals with subjective cognitive impairment (SCI) have an increased risk of developing dementia syndrome. For example, there is evidence suggesting that individuals with SCI, an ApoE4 allele, and age 60+ have about a 25% risk of developing dementia at some point.

In future releases of this algorithm, we will further explore an evidence-based approach to assess individuals with SCI with the goal of identifying the earliest stages of MCI, and determining whether the SCI may be a forerunner of Alzheimer’s Disease.