Boneset, Studies

Antibacterial

Cytotoxicity and antibacterial activity of ethanol extract from leaves of a herbal drug, Boneset (Eupatorium perfoliatum)

Anti-Inflammatory

Anti-inflammatory activity of *Eupatorium perfoliatum* L. extracts, eupafolin, and dimeric guaianolide via iNOS inhibitory activity and modulation of inflammation-related cytokines and chemokines

Antioxidant

Activity-guided Isolation and Identification of Free Radical-scavenging Components from Ethanolic Extract of Boneset (Leaves of Eupatorium Perfoliatum)

Antiviral

Antiviral activity of hydroalcoholic extract from Eupatorium perfoliatum L. against the attachment of influenza A virus

Cardiovascular

Eupafolin ameliorates lipopolysaccharide-induced cardiomyocyte autophagy via PI3K/AKT/mTOR signaling pathway.

Cerebrovascular

Eupafolin alleviates cerebral ischemia/reperfusion injury in rats via blocking the TLR4/NF‑κB signaling pathway.

Homeopathic

• A controlled clinical trial for testing the efficacy of the homeopathic drug eupatorium perfoliatum D2 in the treatment of common cold (author's transl)
• Effects of homeopathic medications Eupatorium perfoliatum and Arsenicum album on parasitemia of Plasmodium berghei-infected mice

Immune System

Immunologically active polysaccharides of Eupatorium cannabinum and Eupatorium perfoliatum

Parasites

• An unusual dimeric guaianolide with antiprotozoal activity and further sesquiterpene lactones from Eupatorium perfoliatum
• Effects of homeopathic medications Eupatorium perfoliatum and Arsenicum album on parasitemia of Plasmodium berghei-infected mice

Other Effects

• Attenuation of Complete Freund's Adjuvant-induced arthritis by different dilutions of *Eupatorium perfoliatum* and Crotalus horridus and their safety evaluation
• Capillary electrophoresis of phenolic compounds from *Eupatorium perfoliatum*L.(Asteraceae)