Sciatica

See Neuralgia ; Sciatic Nerve

The term sciatica describes the symptoms of leg pain—and possibly tingling, numbness, or weakness—that originate in the lower back and travel through the buttock and down the large sciatic nerve in the back of each leg

Sciatica Nerve Pain

Sciatica is often characterized by one or more of the following symptoms:

• Constant pain in only one side of the buttock or leg (rarely in both legs)
• Pain that is worse when sitting
• Leg pain that is often described as burning, tingling, or searing (versus a dull ache)
• Weakness, numbness, or difficulty moving the leg, foot, and/or toes
• A sharp pain that may make it difficult to stand up or walk
• Pain that radiates down the leg and possibly into the foot and toes (it rarely occurs only in the foot)

Sciatic pain can vary from infrequent and irritating to constant and incapacitating. Symptoms are usually based on the location of the pinched nerve.

While symptoms can be painful and potentially debilitating, it is rare that permanent sciatic nerve damage (tissue damage) will result, and spinal cord involvement is possible but rare.

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Articles/Studies

• What You Need to Know About Sciatica
• Drug no Better than Placebo for Sciatica
• IAAM: **Ayurveda** Case studies
• Nanosuspension of **Foeniculum vulgare** promotes accelerated sensory and motor function recovery after sciatic nerve injury.
• Acupuncture** may be effective in treating the pain associated with sciatica.
• Warming **acupuncture** effectively relieves symptoms of sciatica.
• Aloe vera** is an effective neuroprotective against sciatic nerve ischemia/reperfusion injury and was found to be as effective as methylprednisolone.
• Daily consumption of **EGCG** might be effective in the prevention and treatment of secondary damage related to peripheral nerve injury.
• *Genistein** relieves neuropathic pain following chronic sciatic nerve injury in mice.
• Holy basil** (O. sanctum) ameliorates sciatic nerve transection-induced neuropathy in rats.
• Palmitoylethanolamide**, a neutraceutical, in nerve compression syndromes: efficacy and safety in sciatic pain and carpal tunnel syndrome.
• Quercetin** was significantly superior to Gabapentine and morphine in terms of alleviating mechanical and thermal hypersensitivity.
• The Chinese herbal formula: **Qichu Fujin** Recipe stimulates regeneration and repair of injured sciatic nerve in rats.
• The fermented soy product **natto** improves neurobehavioral deficits after sciatic nerve injury in rats.
• Ursolic acid** induced neural regeneration after sciatic nerve injury in mice.
• Chiropractic** manipulation has a therapeutic effect on pain relief for acute back pain and sciatica with disc protrusion.
• Massage therapy** may have a therapeutic role in alleviating symptoms of sciatica and low back pain.
• Sixty percent of patients with sciatica who had failed other medical management benefited from **spinal manipulation** to the same degree as if they underwent surgical intervention.
• An experimental comparison of the effects of **propolis, curcumin, and methylprednisolone** on crush injuries of the sciatic nerve.
• Thiocitic (syn. **Lipoic acid**) and **Acetyl-L-carnitine** reduce sciatic pain caused by a herniated disc.
• Ozone therapy** improved sciatic nerve injury recovery without causing an increase in fibrotic tissue.
• Investigation of the effects of **berberine** on bortezomib-induced sciatic nerve and spinal cord damage.
• Antinociceptive effect of **isoorientin** against neuropathic pain induced by the chronic constriction injury of the sciatic nerve.
• Glycyrrhizic acid** promotes sciatic nerves recovery in type 1 diabetic rats and protects Schwann cells from high glucose-induced cytotoxicity.
• Effects of **apocynin** on sciatic nerve injury.
• Neuroprotective effect of **anethole** against neuropathic pain induced by chronic constriction injury of the sciatic nerve.
• Ameliorative effects of **escin** on neuropathic pain induced by chronic constriction injury of sciatic nerve.
• Combined treatment of rehabilitation and supplements with anti-inflammatory, pain-relieving, and antioxidant action is effective in the treatment of sciatica.