Myonectin (CTRP15)

Myonectin (CTRP15) is a myokine that helps skeletal muscle communicate with other metabolic compartments, such as the liver and adipose tissue. It's also known as C1q/TNF-related protein 15/erythroferrone.

Myonectin is secreted from muscles and adipocytes. Its expression and circulating levels are regulated by: Diet, Metabolic state, Exercise.

Myonectin is an exercise-induced myokine that can help with:

• Suppressing apoptosis
• Suppressing inflammation
• Ameliorating acute ischemic injury in the heart

Myonectin links skeletal muscle to lipid homeostasis in the liver and adipose tissue.

Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis

Myonectin deletion promotes adipose fat storage and reduces liver steatosis