Bleomycin
Videos
Mechanism of Action
Dr. Ghosh on the Role of Bleomycin in Hodgkin Lymphoma
BLOOD CLOTS IN MY LUNG AND BLEOMYCIN LUNG TOXICITY
Another Check Up: CHRONIC Bleomycin Lung Toxicity
Bleomycin is a medication used to treat cancer. This includes Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, ovarian cancer, and cervical cancer among others. Typically used with other cancer medications, it can be given intravenously, by injection into a muscle or under the skin. It may also be administered inside the chest to help prevent the recurrence of a fluid around the lung due to cancer; however talc is better for this.
Common side effects include fever, weight loss, vomiting, and rash. A severe type of anaphylaxis may occur. It may also cause inflammation of the lungs that can result in lung scarring. Chest X-rays every couple of weeks are recommended to check for this. Bleomycin may cause harm to the baby if used during pregnancy. It is believed to primarily work by preventing the making of DNA.
Articles/Studies
Withaferin A attenuates bleomycin-induced scleroderma.
Sesamol attenuates bleomycin-induced pulmonary toxicity and fibrosis.
Baicalein attenuates bleomycin-induced lung fibroblast senescence and lung fibrosis.
Protective effects of alpha-lipoic acid on bleomycin-induced skin fibrosis.
Thymoquinone ameliorates bleomycin-induced reproductive toxicity in male Balb/c mice.
Nigella sativa oil treatment attenuated the effects of bleomycin induced pulmonary fibrosis.
Mangiferin attenuates bleomycin-induced pulmonary fibrosis.
Pachymic acid protects against bleomycin-induced pulmonary fibrosis.
Ellagic acid attenuates bleomycin and cyclophosphamide-induced pulmonary toxicity in Wistar rats.
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis.