Growth Hormone Abnormalities

It has long been known that severe forms of metabolic acidosis in children, such as renal tubular acidosis, are associated with low levels of growth hormone with resultant short stature. Correction of the acidosis with bicarbonate or potassium citrate  increases growth hormone significantly and improved growth. The use of enough potassium bicarbonate in the diet to neutralize the daily net acid load in postmenopausal women resulted in a significant increase in growth hormone and resultant osteocalcin. -  Potassium bicarbonate reduces urinary nitrogen excretion in postmenopausal women

Improving growth hormone levels may improve quality of life, reduce cardiovascular risk factors, improve body composition, and even improve memory and cognition  - Growth hormone and memory

As well this results in a reduction of urinary calcium loss equivalent to 5% of bone calcium content over a period of 3 years. -  Long-term persistence of the urine calcium-lowering effect of potassium bicarbonate in postmenopausal women.