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Orbitofrontal cortex

The orbitofrontal cortex is the area of the prefrontal cortex that sits just above the orbits (also known as the eye sockets). It is thus found at the very front of the brain, and has extensive connections with sensory areas as well as limbic system structures involved in emotion and memory.

Values encoded in orbitofrontal cortex are causally related to economic choices

Brain Cells That Thrive on Uncertainty Help Us Adapt and Learn

Scientists have discovered a group of brain cells in the orbitofrontal cortex that become more active when outcomes are uncertain, revealing how the brain adapts and learns from unpredictable situations. These neurons—found in both rats and humans—help balance flexibility and precision in decision-making, particularly when rewards are inconsistent.

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