6 Immune System
<p>From: <a id="null" class="null" href="https://www.cell.com/cell/pdf/S0092-8674(18)30293-9.pdf">https://www.cell.com/cell/pdf/S0092-8674(18)30293-9.pdf</a></p>
<p>Recent studies indicate that in addition to these classical immune functions, cells of the innate and adaptive immune system also sense complex tissue- and environment-derived signals, including those from the nervous system and the diet. In turn these responses regulate physiologic processes in multiple tissues throughout the body, including nervous system function, metabolic state, thermogenesis, and tissue repair. In this review we propose an integrated view of how the mammalian immune system senses and interacts with other complex organ systems to maintain tissue and whole-body homeostasis. </p>