Open in TheBrain

Babesia microti remodeler

https://veupathdb.org

Apicomplexa/Aconoidasida/Piroplasmida/Babesiidae/

species and hosts

Canine babesiosis is a significant tick-borne disease caused by various species of the protozoan genus Babesia.

Both the large and small forms of Babesia species (B. canis, B. vogeli, B. gibsoni, and B. microti-like isolates also referred to as "B. vulpes" and "Theileria annae") infect dogs in Europe

Blast with human Snf2H ATPase domain

hits 27 proteins

Babesia microti blast to human Snf2H ATPase domain.txt

conclusion: die ATPase domain ist sehr unterschiedlich zur humanen ATPase domain (max51% identity). good target

Questions

which of these remodelers are essential?

which of these remodeler would be screenable - ATPase activity high, in the presence of DNA or DNA+H4 peptide

Attachments