Pre-Clinical work
see ongoing NH125 Plasmodium Inhibitor - next steps pre-clinics
How to progress efficiently through pre-clinics - towards a company
- we need more than one lead compound (best >5). > do an additional, larger screening.
- we need a structure of PfSnf2L with the inhibitor
- we need med-chem
- we need a mouse model
- Optional: Malaria on a chip - disease model